Antitumor activity of LSD1 inhibitors in lung cancer

por Mohammad, Helai P., Kruger, Ryan G.
Publicado 2016

Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island

por O'Hagan, Heather M., Mohammad, Helai P., Baylin, Stephen B.
Publicado 2008

Inhibiting PRMT5 induces DNA damage and increases anti-proliferative activity of Niraparib, a PARP inhibitor, in models of breast and ovarian cancer

por O’Brien, Shane, Butticello, Michael, Thompson, Christine, Wilson, Boris, Wyce, Anastasia, Mahajan, Vivek, Kruger, Ryan, Mohammad, Helai, Fedoriw, Andy
Publicado 2023

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

por Clements, Eriko G., Mohammad, Helai P., Leadem, Benjamin R., Easwaran, Hariharan, Cai, Yi, Van Neste, Leander, Baylin, Stephen B.
Publicado 2012

Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues

por Noto, Paul B., Sikorski, Timothy W., Zappacosta, Francesca, Wagner, Craig D., Montes de Oca, Rocio, Szapacs, Matthew E., Annan, Roland S., Liu, Yan, McHugh, Charles F., Mohammad, Helai P., Piccoli, Steven P., Creasy, Caretha L.
Publicado 2020

Histone Demethylase LSD1 is required for Germinal Center formation and BCL6-driven lymphomagenesis

por Hatzi, Katerina, Geng, Huimin, Doane, Ashley S., Meydan, Cem, LaRiviere, Reed, Cardenas, Mariano, Duy, Cihangir, Shen, Hao, Vidal, Maria Nieves Calvo, Baslan, Timour, Mohammad, Helai P., Kruger, Ryan G., Shaknovich, Rita, Haberman, Ann M., Inghirami, Giorgio, Lowe, Scott W., Melnick, Ari M.
Publicado 2018

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

por Lee, Catherine, Rudneva, Vasilisa A., Erkek, Serap, Zapatka, Marc, Chau, Lianne Q., Tacheva-Grigorova, Silvia K., Garancher, Alexandra, Rusert, Jessica M., Aksoy, Ozlem, Lea, Robin, Mohammad, Helai P., Wang, Jianxun, Weiss, William A., Grimes, H. Leighton, Pfister, Stefan M., Northcott, Paul A., Wechsler-Reya, Robert J.
Publicado 2019

Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subt...

por Smitheman, Kimberly N., Severson, Tesa M., Rajapurkar, Satyajit R., McCabe, Michael T., Karpinich, Natalie, Foley, James, Pappalardi, Melissa B., Hughes, Ashley, Halsey, Wendy, Thomas, Elizabeth, Traini, Christopher, Federowicz, Kelly E., Laraio, Jenny, Mobegi, Fredrick, Ferron-Brady, Geraldine, Prinjha, Rabinder K., Carpenter, Christopher L., Kruger, Ryan G., Wessels, Lodewyk, Mohammad, Helai P.
Publicado 2019

Alterations of immune response of non-small cell lung cancer with Azacytidine

por Wrangle, John, Wang, Wei, Koch, Alexander, Easwaran, Hariharan, Mohammad, Helai P., Vendetti, Frank, VanCriekinge, Wim, DeMeyer, Tim, Du, Zhengzong, Parsana, Princy, Rodgers, Kristen, Yen, Ray-Whay, Zahnow, Cynthia A., Taube, Janis M., Brahmer, Julie R., Tykodi, Scott S., Easton, Keith, Carvajal, Richard D., Jones, Peter A., Laird, Peter W., Weisenberger, Daniel J., Tsai, Salina, Juergens, Rosalyn A., Topalian, Suzanne L., Rudin, Charles M., Brock, Malcolm V., Pardoll, Drew, Baylin, Stephen B.
Publicado 2013

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

por Bell, Charles C., Fennell, Katie A., Chan, Yih-Chih, Rambow, Florian, Yeung, Miriam M., Vassiliadis, Dane, Lara, Luis, Yeh, Paul, Martelotto, Luciano G., Rogiers, Aljosja, Kremer, Brandon E., Barbash, Olena, Mohammad, Helai P., Johanson, Timothy M., Burr, Marian L., Dhar, Arindam, Karpinich, Natalie, Tian, Luyi, Tyler, Dean S., MacPherson, Laura, Shi, Junwei, Pinnawala, Nathan, Yew Fong, Chun, Papenfuss, Anthony T., Grimmond, Sean M., Dawson, Sarah-Jane, Allan, Rhys S., Kruger, Ryan G., Vakoc, Christopher R., Goode, David L., Naik, Shalin H., Gilan, Omer, Lam, Enid Y. N., Marine, Jean-Christophe, Prinjha, Rab K., Dawson, Mark A.
Publicado 2019