Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability

por An, Seong J., Mohanty, Jyotidarsini, Tome, Francisco, Suzuki, Yoshihisa, Lax, Irit, Schlessinger, Joseph
Publicado 2023

Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein

por Park, Joon Sung, Choi, Jungyuen, Cao, Longxing, Mohanty, Jyotidarsini, Suzuki, Yoshihisa, Park, Andy, Baker, David, Schlessinger, Joseph, Lee, Sangwon
Publicado 2022

Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention

por Krimmer, Stefan G., Bertoletti, Nicole, Suzuki, Yoshihisa, Katic, Luka, Mohanty, Jyotidarsini, Shu, Sheng, Lee, Sangwon, Lax, Irit, Mi, Wei, Schlessinger, Joseph
Publicado 2023