Selective DNA methylation in cancers controls collateral damage induced by large structural variations

por Mohanty, Vakul, Akmamedova, Ogulsheker, Komurov, Kakajan
Publicado 2016

Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers

por Mohanty, Vakul, Wang, Fang, Mills, Gordon B., Chen, Ken
Publicado 2021

Sensei: how many samples to tell a change in cell type abundance?

por Liang, Shaoheng, Willis, Jason, Dou, Jinzhuang, Mohanty, Vakul, Huang, Yuefan, Vilar, Eduardo, Chen, Ken
Publicado 2022

Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux

por Huang, Yuefan, Mohanty, Vakul, Dede, Merve, Tsai, Kyle, Daher, May, Li, Li, Rezvani, Katayoun, Chen, Ken
Publicado 2023

A piggyBac-based reporter system for scalable in vitro and in vivo analysis of 3′ untranslated region-mediated gene regulation

por Chaudhury, Arindam, Kongchan, Natee, Gengler, Jon P., Mohanty, Vakul, Christiansen, Audrey E., Fachini, Joseph M., Martin, James F., Neilson, Joel R.
Publicado 2014

MEDALT: single-cell copy number lineage tracing enabling gene discovery

por Wang, Fang, Wang, Qihan, Mohanty, Vakul, Liang, Shaoheng, Dou, Jinzhuang, Han, Jincheng, Minussi, Darlan Conterno, Gao, Ruli, Ding, Li, Navin, Nicholas, Chen, Ken
Publicado 2021

Bi-order multimodal integration of single-cell data

por Dou, Jinzhuang, Liang, Shaoheng, Mohanty, Vakul, Miao, Qi, Huang, Yuefan, Liang, Qingnan, Cheng, Xuesen, Kim, Sangbae, Choi, Jongsu, Li, Yumei, Li, Li, Daher, May, Basar, Rafet, Rezvani, Katayoun, Chen, Rui, Chen, Ken
Publicado 2022

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

por Modur, Vishnu, Singh, Navneet, Mohanty, Vakul, Chung, Eunah, Muhammad, Belal, Choi, Kwangmin, Chen, Xiaoting, Chetal, Kashish, Ratner, Nancy, Salomonis, Nathan, Weirauch, Matthew T., Waltz, Susan, Huang, Gang, Privette-Vinnedge, Lisa, Park, Joo-Seop, Janssen, Edith M., Komurov, Kakajan
Publicado 2018

Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes

por Abbas, Hussein A., Mohanty, Vakul, Wang, Ruiping, Huang, Yuefan, Liang, Shaoheng, Wang, Feng, Zhang, Jianhua, Qiu, Yihua, Hu, Chenyue W., Qutub, Amina A., Dail, Monique, Bolen, Christopher R., Daver, Naval, Konopleva, Marina, Futreal, Andrew, Chen, Ken, Wang, Linghua, Kornblau, Steven M.
Publicado 2021

KLF5 governs sphingolipid metabolism and barrier function of the skin

por Lyu, Ying, Guan, Yinglu, Deliu, Lisa, Humphrey, Ericka, Frontera, Joanna K., Yang, Youn Joo, Zamler, Daniel, Kim, Kun Hee, Mohanty, Vakul, Jin, Kevin, Liu, Virginia, Dou, Jinzhuang, Veillon, Lucas J., Kumar, Shwetha V., Lorenzi, Philip L., Chen, Yang, McAndrews, Kathleen M., Grivennikov, Sergei, Song, Xingzhi, Zhang, Jianhua, Xi, Yuanxin, Wang, Jing, Chen, Ken, Nagarajan, Priyadharsini, Ge, Yejing
Publicado 2022

GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells

por Liu, Enli, Ang, Sonny O. T., Kerbauy, Lucila, Basar, Rafet, Kaur, Indreshpal, Kaplan, Mecit, Li, Li, Tong, Yijiu, Daher, May, Ensley, Emily L., Uprety, Nadima, Nunez Cortes, Ana Karen, Yang, Ryan Z., Li, Ye, Shaim, Hila, Reyes Silva, Francia, Lin, Paul, Mohanty, Vakul, Acharya, Sunil, Shanley, Mayra, Muniz-Feliciano, Luis, Banerjee, Pinaki P., Chen, Ken, Champlin, Richard E., Shpall, Elizabeth J., Rezvani, Katayoun
Publicado 2021

Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

por Li, Li, Mohanty, Vakul, Dou, Jinzhuang, Huang, Yuefan, Banerjee, Pinaki P., Miao, Qi, Lohr, Jens G., Vijaykumar, Tushara, Frede, Julia, Knoechel, Birgit, Muniz-Feliciano, Luis, Laskowski, Tamara J., Liang, Shaoheng, Moyes, Judy S., Nandivada, Vandana, Basar, Rafet, Kaplan, Mecit, Daher, May, Liu, Enli, Li, Ye, Acharya, Sunil, Lin, Paul, Shanley, Mayra, Rafei, Hind, Marin, David, Mielke, Stephan, Champlin, Richard E., Shpall, Elizabeth J., Chen, Ken, Rezvani, Katayoun
Publicado 2023

Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD

por Mendt, Mayela, Daher, May, Basar, Rafet, Shanley, Mayra, Kumar, Bijender, Wei Inng, Francesca Lim, Acharya, Sunil, Shaim, Hila, Fowlkes, Natalie, Tran, Jamie P., Gokdemir, Elif, Uprety, Nadima, Nunez-Cortes, Ana K., Ensley, Emily, Mai, Thao, Kerbauy, Lucila N., Melo-Garcia, Luciana, Lin, Paul, Shen, Yifei, Mohanty, Vakul, Lu, JunJun, Li, Sufang, Nandivada, Vandana, Wang, Jing, Banerjee, Pinaki, Reyes-Silva, Francia, Liu, Enli, Ang, Sonny, Gilbert, April, Li, Ye, Wan, Xinhai, Gu, Jun, Zhao, Ming, Baran, Natalia, Muniz-Feliciano, Luis, Wilson, Jeffrey, Kaur, Indreshpal, Gagea, Mihai, Konopleva, Marina, Marin, David, Tang, Guilin, Chen, Ken, Champlin, Richard, Rezvani, Katayoun, Shpall, Elizabeth J.
Publicado 2021