Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants

por Mohedas, Agustin H., Wang, You, Sanvitale, Caroline E., Canning, Peter, Choi, Sungwoon, Xing, Xuechao, Bullock, Alex N., Cuny, Gregory D., Yu, Paul B.
Publicado 2014

A New Class of Small Molecule Inhibitor of BMP Signaling

por Sanvitale, Caroline E., Kerr, Georgina, Chaikuad, Apirat, Ramel, Marie-Christine, Mohedas, Agustin H., Reichert, Sabine, Wang, You, Triffitt, James T., Cuny, Gregory D., Yu, Paul B., Hill, Caroline S., Bullock, Alex N.
Publicado 2013

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva

por Williams, Eleanor, Bagarova, Jana, Kerr, Georgina, Xia, Dong-Dong, Place, Elsie S., Dey, Devaveena, Shen, Yue, Bocobo, Geoffrey A., Mohedas, Agustin H., Huang, Xiuli, Sanderson, Philip E., Lee, Arthur, Zheng, Wei, Economides, Aris N., Smith, James C., Yu, Paul B., Bullock, Alex N.
Publicado 2021