Obesity genes: so close and yet so far...

por Pomp, Daniel, Mohlke, Karen L
Publicado 2008

Association of FTO With Obesity-Related Traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort

por Marvelle, Amanda F., Lange, Leslie A., Qin, Li, Adair, Linda S., Mohlke, Karen L.
Publicado 2008

Allele-Specific Transcriptional Activity at Type 2 Diabetes–Associated Single Nucleotide Polymorphisms in Regions of Pancreatic Islet Open Chromatin at the JAZF1 Locus

por Fogarty, Marie P., Panhuis, Tami M., Vadlamudi, Swarooparani, Buchkovich, Martin L., Mohlke, Karen L.
Publicado 2013

Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus

por Fogarty, Marie P., Cannon, Maren E., Vadlamudi, Swarooparani, Gaulton, Kyle J., Mohlke, Karen L.
Publicado 2014

Removing reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci

por Buchkovich, Martin L., Eklund, Karl, Duan, Qing, Li, Yun, Mohlke, Karen L., Furey, Terrence S.
Publicado 2015

Association Studies with Imputed Variants Using Expectation-Maximization Likelihood-Ratio Tests

por Huang, Kuan-Chieh, Sun, Wei, Wu, Ying, Chen, Mengjie, Mohlke, Karen L., Lange, Leslie A., Li, Yun
Publicado 2014

Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs

por Zhong, Wujuan, Dong, Li, Poston, Taylor B., Darville, Toni, Spracklen, Cassandra N., Wu, Di, Mohlke, Karen L., Li, Yun, Li, Quefeng, Zheng, Xiaojing
Publicado 2020

INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

por Liu, Yan, Sanoff, Hanna K., Cho, Hyunsoon, Burd, Christin E., Torrice, Chad, Mohlke, Karen L., Ibrahim, Joseph G., Thomas, Nancy E., Sharpless, Norman E.
Publicado 2009

Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

por Perrin, Hannah J., Currin, Kevin W., Vadlamudi, Swarooparani, Pandey, Gautam K., Ng, Kenneth K., Wabitsch, Martin, Laakso, Markku, Love, Michael I., Mohlke, Karen L.
Publicado 2021

Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health

por Young, Kristin L., Graff, Misa, North, Kari E., Richardson, Andrea S., Mohlke, Karen L., Lange, Leslie A., Lange, Ethan M., Harris, Kathleen M., Gordon-Larsen, Penny
Publicado 2015

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

por Orchard, Peter, Manickam, Nandini, Ventresca, Christa, Vadlamudi, Swarooparani, Varshney, Arushi, Rai, Vivek, Kaplan, Jeremy, Lalancette, Claudia, Mohlke, Karen L., Gallagher, Katherine, Burant, Charles F., Parker, Stephen C.J.
Publicado 2021

Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

por Cannon, Maren E., Currin, Kevin W., Young, Kristin L., Perrin, Hannah J., Vadlamudi, Swarooparani, Safi, Alexias, Song, Lingyun, Wu, Ying, Wabitsch, Martin, Laakso, Markku, Crawford, Gregory E., Mohlke, Karen L.
Publicado 2019

Wnt activity reveals context-specific genetic effects on gene regulation in neural progenitors

por Matoba, Nana, Le, Brandon D, Valone, Jordan M, Wolter, Justin M, Mory, Jessica, Liang, Dan, Aygün, Nil, Broadaway, K Alaine, Bond, Marielle L, Mohlke, Karen L, Zylka, Mark J, Love, Michael I, Stein, Jason L
Publicado 2023

A map of open chromatin in human pancreatic islets

por Gaulton, Kyle J., Nammo, Takao, Pasquali, Lorenzo, Simon, Jeremy M., Giresi, Paul G., Fogarty, Marie P., Panhuis, Tami M., Mieczkowski, Piotr, Secchi, Antonio, Bosco, Domenico, Berney, Thierry, Montanya, Eduard, Mohlke, Karen L., Lieb, Jason D., Ferrer, Jorge
Publicado 2010

Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans

por Garske, Kristina M., Pan, David Z., Miao, Zong, Bhagat, Yash V., Comenho, Caroline, Robles, Christopher R., Benhammou, Jihane N., Alvarez, Marcus, Ko, Arthur, Ye, Chun Jimmie, Pisegna, Joseph R., Mohlke, Karen L., Sinsheimer, Janet S., Laakso, Markku, Pajukanta, Päivi
Publicado 2019

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

por Cannon, Maren E., Duan, Qing, Wu, Ying, Zeynalzadeh, Monica, Xu, Zheng, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Civelek, Mete, Lusis, Aldons J., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Tang, Hua, Laakso, Markku, Li, Yun, Mohlke, Karen L.
Publicado 2017

The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance

por Miao, Zong, Alvarez, Marcus, Ko, Arthur, Bhagat, Yash, Rahmani, Elior, Jew, Brandon, Heinonen, Sini, Muñoz-Hernandez, Linda Liliana, Herrera-Hernandez, Miguel, Aguilar-Salinas, Carlos, Tusie-Luna, Teresa, Mohlke, Karen L., Laakso, Markku, Pietiläinen, Kirsi H., Halperin, Eran, Pajukanta, Päivi
Publicado 2020

Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men

por Mahendran, Yuvaraj, Vangipurapu, Jagadish, Cederberg, Henna, Stančáková, Alena, Pihlajamäki, Jussi, Soininen, Pasi, Kangas, Antti J., Paananen, Jussi, Civelek, Mete, Saleem, Niyas K., Pajukanta, Päivi, Lusis, Aldons J., Bonnycastle, Lori L., Morken, Mario A., Collins, Francis S., Mohlke, Karen L., Boehnke, Michael, Ala-Korpela, Mika, Kuusisto, Johanna, Laakso, Markku
Publicado 2013

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Publicado 2018

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

por Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Publicado 2018