Survival and new-onset morbidity after critical care admission for acute pancreatitis in Scotland: a national electronic healthcare record linkage cohort study

por Ventre, Chiara, Nowell, Sian, Graham, Catriona, Kidd, Doug, Skouras, Christos, Mole, Damian J
Publicado 2018

Increased risk of type 3c diabetes mellitus after acute pancreatitis warrants a personalized approach including diabetes screening

por Walker, Alexander, O’Kelly, James, Graham, Catriona, Nowell, Sian, Kidd, Doug, Mole, Damian J
Publicado 2022

Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques

por Shave, Steven, McGuire, Kris, Pham, Nhan T., Mole, Damian J., Webster, Scott P., Auer, Manfred
Publicado 2018

Evaluation of plasma microRNA-122, high-mobility group box 1 and keratin-18 concentrations to stratify acute gallstone disease: a pilot observational cohort study in an emergency g...

por Th’ng, Francesca, Vliegenthart, Bastiaan, Lea, Jonathan D, Antoine, Daniel J, Dear, James W, Mole, Damian J
Publicado 2018

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury

por Zheng, Xiaozhong, Zhang, Ailiang, Binnie, Margaret, McGuire, Kris, Webster, Scott P., Hughes, Jeremy, Howie, Sarah E. M., Mole, Damian J.
Publicado 2019

Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct

por Stimson, Roland H., Anderson, Anna J., Ramage, Lynne E., Macfarlane, David P., de Beaux, Andrew C., Mole, Damian J., Andrew, Ruth, Walker, Brian R.
Publicado 2017

Quantitative multiparametric MRI allows safe surgical planning in patients undergoing liver resection for colorectal liver metastases: report of two patients

por Sethi, Pulkit, Thavanesan, Navamayooran, Welsh, Fenella KS, Connell, John, Pickles, Elisabeth, Kelly, Matt, Fallowfield, Jonathan A, Kendall, Timothy J, Mole, Damian J, Rees, Myrddin
Publicado 2021

Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

por Puigoriol-Illamola, Dolors, Companys-Alemany, Júlia, McGuire, Kris, Homer, Natalie Z. M., Leiva, Rosana, Vázquez, Santiago, Mole, Damian J., Griñán-Ferré, Christian, Pallàs, Mercè
Publicado 2021

Co-treatments to Boost IDO Activity and Inhibit Production of Downstream Catabolites Induce Durable Suppression of Experimental Autoimmune Encephalomyelitis

por Lemos, Henrique, Mohamed, Eslam, Ou, Rong, McCardle, Caroline, Zheng, Xiaozhong, McGuire, Kris, Homer, Natalie Z. M., Mole, Damian J., Huang, Lei, Mellor, Andrew L.
Publicado 2020

Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma

por Rad Pour, Soudabeh, Morikawa, Hiromasa, Kiani, Narsis A., Gomez-Cabrero, David, Hayes, Alistair, Zheng, Xiaozhong, Pernemalm, Maria, Lehtiö, Janne, Mole, Damian J., Hansson, Johan, Eriksson, Hanna, Tegnér, Jesper
Publicado 2020

Identifying risk factors for progression to critical care admission and death among individuals with acute pancreatitis: a record linkage analysis of Scottish healthcare databases

por Mole, Damian J, Gungabissoon, Usha, Johnston, Philip, Cochrane, Lynda, Hopkins, Leanne, Wyper, Grant M A, Skouras, Christos, Dibben, Chris, Sullivan, Frank, Morris, Andrew, Ward, Hester J T, Lawton, Andrew M, Donnan, Peter T
Publicado 2016

Study protocol: HepaT1ca – an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies

por Mole, Damian J., Fallowfield, Jonathan A., Kendall, Timothy J., Welsh, Fenella, Semple, Scott I., Bachtiar, Velicia, Kelly, Matt, Wigmore, Stephen J., James Garden, O., Wilman, Henry R., Banerjee, Rajarshi, Rees, Myrddin, Brady, Michael
Publicado 2018

Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase

por Hutchinson, Jonathan P., Rowland, Paul, Taylor, Mark R. D., Christodoulou, Erica M., Haslam, Carl, Hobbs, Clare I., Holmes, Duncan S., Homes, Paul, Liddle, John, Mole, Damian J., Uings, Iain, Walker, Ann L., Webster, Scott P., Mowat, Christopher G., Chung, Chun-wa
Publicado 2017

Quantitative magnetic resonance imaging predicts individual future liver performance after liver resection for cancer

por Mole, Damian J., Fallowfield, Jonathan A., Sherif, Ahmed E., Kendall, Timothy, Semple, Scott, Kelly, Matt, Ridgway, Gerard, Connell, John J., McGonigle, John, Banerjee, Rajarshi, Brady, J. Michael, Zheng, Xiaozhong, Hughes, Michael, Neyton, Lucile, McClintock, Joanne, Tucker, Garry, Nailon, Hilary, Patel, Dilip, Wackett, Anthony, Steven, Michelle, Welsh, Fenella, Rees, Myrddin
Publicado 2020

Study protocol for resolution of organ injury in acute pancreatitis (RESORP): an observational prospective cohort study

por Sherif, Ahmed E, McFadyen, Rory, Boyd, Julia, Ventre, Chiara, Glenwright, Margaret, Walker, Kim, Zheng, Xiaozhong, White, Audrey, McFadyen, Laura, Connon, Emma, Damaskos, Dimitrios, Steven, Michelle, Wackett, Anthony, Thomson, Euan, Cameron, David C, MacLeod, Jill, Baxter, Shaun, Semple, Scott, Morris, David, Clark-Stewart, Saskia, Graham, Catriona, Mole, Damian J
Publicado 2020

Increased levels of 3-hydroxykynurenine parallel disease severity in human acute pancreatitis

por Skouras, Christos, Zheng, Xiaozhong, Binnie, Margaret, Homer, Natalie Z. M., Murray, Toby B. J., Robertson, Darren, Briody, Lesley, Paterson, Finny, Spence, Heather, Derr, Lisa, Hayes, Alastair J., Tsoumanis, Andreas, Lyster, Dawn, Parks, Rowan W., Garden, O. James, Iredale, John P., Uings, Iain J., Liddle, John, Wright, Wayne L., Dukes, George, Webster, Scott P., Mole, Damian J.
Publicado 2016

Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

por Dobie, Ross, Wilson-Kanamori, John R., Henderson, Beth E.P., Smith, James R., Matchett, Kylie P., Portman, Jordan R., Wallenborg, Karolina, Picelli, Simone, Zagorska, Anna, Pendem, Swetha V., Hudson, Thomas E., Wu, Minnie M., Budas, Grant R., Breckenridge, David G., Harrison, Ewen M., Mole, Damian J., Wigmore, Stephen J., Ramachandran, Prakash, Ponting, Chris P., Teichmann, Sarah A., Marioni, John C., Henderson, Neil C.
Publicado 2019

Kynurenine–3–monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

por Mole, Damian J, Webster, Scott P, Uings, Iain, Zheng, Xiaozhong, Binnie, Margaret, Wilson, Kris, Hutchinson, Jonathan P, Mirguet, Olivier, Walker, Ann, Beaufils, Benjamin, Ancellin, Nicolas, Trottet, Lionel, Bénéton, Véronique, Mowat, Christopher G, Wilkinson, Martin, Rowland, Paul, Haslam, Carl, McBride, Andrew, Homer, Natalie ZM, Baily, James E, Sharp, Matthew GF, Garden, O James, Hughes, Jeremy, Howie, Sarah EM, Holmes, Duncan S, Liddle, John, Iredale, John P
Publicado 2016

Prostaglandin E(2) promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells

por Crittenden, Siobhan, Goepp, Marie, Pollock, Jolinda, Robb, Calum T., Smyth, Danielle J., Zhou, You, Andrews, Robert, Tyrrell, Victoria, Gkikas, Konstantinos, Adima, Alexander, O’Connor, Richard A., Davies, Luke, Li, Xue-Feng, Yao, Hatti X., Ho, Gwo-Tzer, Zheng, Xiaozhong, Mair, Amil, Vermeren, Sonja, Qian, Bin-Zhi, Mole, Damian J., Gerasimidis, Konstantinos, Schwarze, Jürgen K. J., Breyer, Richard M., Arends, Mark J., O’Donnell, Valerie B., Iredale, John P., Anderton, Stephen M., Narumiya, Shuh, Maizels, Rick M., Rossi, Adriano G., Howie, Sarah E., Yao, Chengcan
Publicado 2021