Hypoxic regulation of the noncoding genome and NEAT1

por Choudhry, Hani, Mole, David R.
Publicado 2016

Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect

por Kindrick, Jessica D., Mole, David R.
Publicado 2020

Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma

por Purshouse, Karin, Chamberlain, Sarah, Soares, Maria, Tuthill, Mark, Protheroe, Andrew, Mole, David R.
Publicado 2019

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma

por Lafleur, Véronique N, Halim, Silvia, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Publicado 2023

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

por Lombardi, Olivia, Li, Ran, Halim, Silvia, Choudhry, Hani, Ratcliffe, Peter J., Mole, David R.
Publicado 2022

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

por Mole, David R., Blancher, Christine, Copley, Richard R., Pollard, Patrick J., Gleadle, Jonathan M., Ragoussis, Jiannis, Ratcliffe, Peter J.
Publicado 2009

Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer

por Choudhry, Hani, Schodel, Johannes, Albukhari, Ashwag, Oikonomopoulos, Spyros, Haider, Syed, Buffa, Francesca, Ragousis, Ioannis, Mole, David R, Harris, Adrian L
Publicado 2014

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

por Choudhry, Hani, Schödel, Johannes, Oikonomopoulos, Spyros, Camps, Carme, Grampp, Steffen, Harris, Adrian L, Ratcliffe, Peter J, Ragoussis, Jiannis, Mole, David R
Publicado 2014

Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

por Platt, James L, Salama, Rafik, Smythies, James, Choudhry, Hani, Davies, James OJ, Hughes, Jim R, Ratcliffe, Peter J, Mole, David R
Publicado 2016

MITF controls the TCA cycle to modulate the melanoma hypoxia response

por Louphrasitthiphol, Pakavarin, Ledaki, Ioanna, Chauhan, Jagat, Falletta, Paola, Siddaway, Robert, Buffa, Francesca M., Mole, David R., Soga, Tomoyoshi, Goding, Colin R.
Publicado 2019

Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer

por Schmid, Virginia, Lafleur, Veronique N., Lombardi, Olivia, Li, Ran, Salama, Rafik, Colli, Leandro, Choudhry, Hani, Chanock, Stephen, Ratcliffe, Peter J., Mole, David R.
Publicado 2019

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

por Schödel, Johannes, Bardella, Chiara, Sciesielski, Lina K, Brown, Jill M, Pugh, Chris W, Buckle, Veronica, Tomlinson, Ian P, Ratcliffe, Peter J, Mole, David R
Publicado 2012

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping

por Schörg, Alexandra, Santambrogio, Sara, Platt, James L., Schödel, Johannes, Lindenmeyer, Maja T., Cohen, Clemens D., Schrödter, Katrin, Mole, David R., Wenger, Roland H., Hoogewijs, David
Publicado 2015

Distal and proximal hypoxia response elements co-operate to regulate organ-specific erythropoietin gene expression

por Orlando, Ilaria M. C., Lafleur, Véronique N., Storti, Federica, Spielmann, Patrick, Crowther, Lisa, Santambrogio, Sara, Schödel, Johannes, Hoogewijs, David, Mole, David R., Wenger, Roland H.
Publicado 2019

Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer

por Choudhry, Hani, Schodel, Johannes, Albukhari, Ashwag, Oikonomopoulos, Spyros, Haider, Syed, Moralli, Daniela, Camps, Carme, Buffa, Francesca, Ratcliffe, Peter, Ragousis, Ioannis, Mole, David R, Harris, Adrian L
Publicado 2014

Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

por Smythies, James A, Sun, Min, Masson, Norma, Salama, Rafik, Simpson, Peter D, Murray, Elizabeth, Neumann, Viviana, Cockman, Matthew E, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Publicado 2018

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

por Grampp, Steffen, Schmid, Virginia, Salama, Rafik, Lauer, Victoria, Kranz, Franziska, Platt, James L., Smythies, James, Choudhry, Hani, Goppelt-Struebe, Margarete, Ratcliffe, Peter J., Mole, David R., Schödel, Johannes
Publicado 2017

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

por Chan, Mun Chiang, Ilott, Nicholas E., Schödel, Johannes, Sims, David, Tumber, Anthony, Lippl, Kerstin, Mole, David R., Pugh, Christopher W., Ratcliffe, Peter J., Ponting, Chris P., Schofield, Christopher J.
Publicado 2016

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

por Grampp, Steffen, Platt, James L., Lauer, Victoria, Salama, Rafik, Kranz, Franziska, Neumann, Viviana K., Wach, Sven, Stöhr, Christine, Hartmann, Arndt, Eckardt, Kai-Uwe, Ratcliffe, Peter J., Mole, David R., Schödel, Johannes
Publicado 2016

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI

por Lauer, Victoria, Grampp, Steffen, Platt, James, Lafleur, Veronique, Lombardi, Olivia, Choudhry, Hani, Kranz, Franziska, Hartmann, Arndt, Wullich, Bernd, Yamamoto, Atsushi, Coleman, Mathew L., Ratcliffe, Peter J., Mole, David R., Schödel, Johannes
Publicado 2020