Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy

por De Pasquale, Valeria, Moles, Anna, Pavone, Luigi Michele
Publicado 2020

Oleoylethanolamide: A Novel Potential Pharmacological Alternative to Cannabinoid Antagonists for the Control of Appetite

por Romano, Adele, Coccurello, Roberto, Giacovazzo, Giacomo, Bedse, Gaurav, Moles, Anna, Gaetani, Silvana
Publicado 2014

Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity

por Moles, Anna, Torres, Sandra, Baulies, Anna, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.
Publicado 2018

In-depth characterization of breast cancer tumor-promoting cell transcriptome by RNA sequencing and microarrays

por Callari, Maurizio, Guffanti, Alessandro, Soldà, Giulia, Merlino, Giuseppe, Fina, Emanuela, Brini, Elena, Moles, Anna, Cappelletti, Vera, Daidone, Maria Grazia
Publicado 2015

The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease

por Cocchiaro, Pasquale, De Pasquale, Valeria, Della Morte, Rossella, Tafuri, Simona, Avallone, Luigi, Pizard, Anne, Moles, Anna, Pavone, Luigi Michele
Publicado 2017

NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake

por Alari-Pahissa, Elisenda, Ataya, Michelle, Moraitis, Ilias, Campos-Ruiz, Miriam, Altadill, Mireia, Muntasell, Aura, Moles, Anna, López-Botet, Miguel
Publicado 2021

Histone Modifications in a Mouse Model of Early Adversities and Panic Disorder: Role for Asic1 and Neurodevelopmental Genes

por Cittaro, Davide, Lampis, Valentina, Luchetti, Alessandra, Coccurello, Roberto, Guffanti, Alessandro, Felsani, Armando, Moles, Anna, Stupka, Elia, D’ Amato, Francesca R., Battaglia, Marco
Publicado 2016

Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury

por Cocchiaro, Pasquale, Fox, Christopher, Tregidgo, Nicholas W., Howarth, Rachel, Wood, Katrina M., Situmorang, Gerhard R., Pavone, Luigi M., Sheerin, Neil S., Moles, Anna
Publicado 2016

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation

por de Mingo, Álvaro, de Gregorio, Estefanía, Moles, Anna, Tarrats, Núria, Tutusaus, Anna, Colell, Anna, Fernandez-Checa, Jose C, Morales, Albert, Marí, Montserrat
Publicado 2016

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

por Martínez-Fábregas, Jonathan, Prescott, Alan, van Kasteren, Sander, Pedrioli, Deena Leslie, McLean, Irwin, Moles, Anna, Reinheckel, Thomas, Poli, Valeria, Watts, Colin
Publicado 2018

Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease

por Fox, Christopher, Cocchiaro, Pasquale, Oakley, Fiona, Howarth, Rachel, Callaghan, Krystena, Leslie, Jack, Luli, Saimir, Wood, Katrina M., Genovese, Federica, Sheerin, Neil S., Moles, Anna
Publicado 2016

The NF-κB1 is a key regulator of acute but not chronic renal injury

por Fearn, Amy, Situmorang, Gerhard R, Fox, Christopher, Oakley, Fiona, Howarth, Rachel, Wilson, Caroline L, Kiosia, Agklinta, Robson, Michael G, Mann, Derek A, Moles, Anna, Sheerin, Neil S
Publicado 2017

Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members

por Megiorni, Francesca, Cialfi, Samantha, McDowell, Heather P, Felsani, Armando, Camero, Simona, Guffanti, Alessandro, Pizer, Barry, Clerico, Anna, De Grazia, Alessandra, Pizzuti, Antonio, Moles, Anna, Dominici, Carlo
Publicado 2014

Whole exome data prioritization unveils the hidden weight of Mendelian causes of male infertility. A report from the first Italian cohort

por Quarantani, Gioia, Sorgente, Anna, Alfano, Massimo, Pipitone, Giovanni Battista, Boeri, Luca, Pozzi, Edoardo, Belladelli, Federico, Pederzoli, Filippo, Ferrara, Anna Maria, Montorsi, Francesco, Moles, Anna, Carrera, Paola, Salonia, Andrea, Casari, Giorgio
Publicado 2023

Unstable Maternal Environment, Separation Anxiety, and Heightened CO(2) Sensitivity Induced by Gene-by-Environment Interplay

por D'Amato, Francesca R., Zanettini, Claudio, Lampis, Valentina, Coccurello, Roberto, Pascucci, Tiziana, Ventura, Rossella, Puglisi-Allegra, Stefano, Spatola, Chiara A. M., Pesenti-Gritti, Paola, Oddi, Diego, Moles, Anna, Battaglia, Marco
Publicado 2011

Transient Exposure to Low Levels of Insecticide Affects Metabolic Networks of Honeybee Larvae

por Derecka, Kamila, Blythe, Martin J., Malla, Sunir, Genereux, Diane P., Guffanti, Alessandro, Pavan, Paolo, Moles, Anna, Snart, Charles, Ryder, Thomas, Ortori, Catharine A., Barrett, David A., Schuster, Eugene, Stöger, Reinhard
Publicado 2013

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse

por Moles, Anna, Murphy, Lindsay, Wilson, Caroline L., Chakraborty, Jayashree Bagchi, Fox, Christopher, Park, Eek Joong, Mann, Jelena, Oakley, Fiona, Howarth, Rachel, Brain, John, Masson, Steven, Karin, Michael, Seki, Ekihiro, Mann, Derek A.
Publicado 2014

A sketch of known and novel MYCN-associated miRNA networks in neuroblastoma

por Megiorni, Francesca, Colaiacovo, Moreno, Cialfi, Samantha, McDowell, Heather P., Guffanti, Alessandro, Camero, Simona, Felsani, Armando, Losty, Paul D., Pizer, Barry, Shukla, Rajeev, Cappelli, Carlo, Ferrara, Eva, Pizzuti, Antonio, Moles, Anna, Dominici, Carlo
Publicado 2017

The transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences...

por Fazi, Barbara, Felsani, Armando, Grassi, Luigi, Moles, Anna, D'Andrea, Daniel, Toschi, Nicola, Sicari, Daria, De Bonis, Pasquale, Anile, Carmelo, Guerrisi, Maria Giovanna, Luca, Emilia, Farace, Maria Giulia, Maira, Giulio, Ciafré, Silvia Anna, Mangiola, Annunziato
Publicado 2015

Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking the Innate Immune Response

por Moles, Anna, Sanchez, Ana M, Banks, Paul S, Murphy, Lindsay B, Luli, Saimir, Borthwick, Lee, Fisher, Andrew, O’Reilly, Steven, van Laar, Jacob M, White, Steven A, Perkins, Neil D, Burt, Alastair D, Mann, Derek A, Oakley, Fiona
Publicado 2013