Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency

por Riba, Marta, del Valle, Jaume, Molina-Porcel, Laura, Pelegrí, Carme, Vilaplana, Jordi
Publicado 2022

Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer’s disease patients

por Riba, Marta, del Valle, Jaume, Romera, Clara, Alsina, Raquel, Molina-Porcel, Laura, Pelegrí, Carme, Vilaplana, Jordi
Publicado 2023

Teaching case 3-2019: Are nuclear clefts or invaginations the niche of intranuclear inclusions in FTLD-TDP?

por Molina-Porcel, Laura, Pérez-Navarro, Esther, García-Forn, Marta, Westaway, David , Colom-Cadena, Martí, Gelpi, Ellen
Publicado 2019

Corpora Amylacea in the Human Brain Exhibit Neoepitopes of a Carbohydrate Nature

por Riba, Marta, Augé, Elisabet, Tena, Iraida, del Valle, Jaume, Molina-Porcel, Laura, Ximelis, Teresa, Vilaplana, Jordi, Pelegrí, Carme
Publicado 2021

Exploration of SUMO2/3 Expression Levels and Autophagy Process in Fragile X-Associated Tremor/Ataxia Syndrome: Addressing Study Limitations and Insights for Future Research

por Alvarez-Mora, Maria Isabel, Garrabou, Glòria, Molina-Porcel, Laura, Grillo-Risco, Ruben, Garcia-Garcia, Francisco, Barcos, Tamara, Cantó-Santos, Judith, Rodriguez-Revenga, Laia
Publicado 2023

Corpora amylacea act as containers that remove waste products from the brain

por Riba, Marta, Augé, Elisabet, Campo-Sabariz, Joan, Moral-Anter, David, Molina-Porcel, Laura, Ximelis, Teresa, Ferrer, Ruth, Martín-Venegas, Raquel, Pelegrí, Carme, Vilaplana, Jordi
Publicado 2019

Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope

por Kang, Sang-Gyun, Han, Zhuang Zhuang, Daude, Nathalie, McNamara, Emily, Wohlgemuth, Serene, Molina-Porcel, Laura, Safar, Jiri G., Mok, Sue-Ann, Westaway, David
Publicado 2021

Pilot Study of the Effects of Chronic Intracerebroventricular Infusion of Human Anti-IgLON5 Disease Antibodies in Mice

por Alvente, Sara, Matteoli, Gabriele, Molina-Porcel, Laura, Landa, Jon, Alba, Mercedes, Bastianini, Stefano, Berteotti, Chiara, Graus, Francesc, Lo Martire, Viviana, Sabater, Lidia, Zoccoli, Giovanna, Silvani, Alessandro
Publicado 2022

Wasteosomes (corpora amylacea) of human brain can be phagocytosed and digested by macrophages

por Riba, Marta, Campo-Sabariz, Joan, Tena, Iraida, Molina-Porcel, Laura, Ximelis, Teresa, Calvo, Maria, Ferrer, Ruth, Martín-Venegas, Raquel, del Valle, Jaume, Vilaplana, Jordi, Pelegrí, Carme
Publicado 2022

Interrupted CAG expansions in ATXN2 gene expand the genetic spectrum of frontotemporal dementias

por Fournier, Clémence, Anquetil, Vincent, Camuzat, Agnès, Stirati-Buron, Sandrine, Sazdovitch, Véronique, Molina-Porcel, Laura, Turbant, Sabrina, Rinaldi, Daisy, Sánchez-Valle, Raquel, Barbier, Mathieu, Latouche, Morwena, Stevanin, Giovanni, Seilhean, Danielle, Brice, Alexis, Duyckaerts, Charles, Le Ber, Isabelle
Publicado 2018

Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis

por Dols-Icardo, Oriol, Montal, Víctor, Sirisi, Sònia, López-Pernas, Gema, Cervera-Carles, Laura, Querol-Vilaseca, Marta, Muñoz, Laia, Belbin, Olivia, Alcolea, Daniel, Molina-Porcel, Laura, Pegueroles, Jordi, Turón-Sans, Janina, Blesa, Rafael, Lleó, Alberto, Fortea, Juan, Rojas-García, Ricard, Clarimón, Jordi
Publicado 2020

Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation

por Daude, Nathalie, Kim, Chae, Kang, Sang-Gyun, Eskandari-Sedighi, Ghazaleh, Haldiman, Tracy, Yang, Jing, Fleck, Shelaine C., Gomez-Cardona, Erik, Han, Zhuang Zhuang, Borrego-Ecija, Sergi, Wohlgemuth, Serene, Julien, Olivier, Wille, Holger, Molina-Porcel, Laura, Gelpi, Ellen, Safar, Jiri G., Westaway, David
Publicado 2020

Cognitive decline in amyotrophic lateral sclerosis: Neuropathological substrate and genetic determinants

por Borrego‐Écija, Sergi, Turon‐Sans, Janina, Ximelis, Teresa, Aldecoa, Iban, Molina‐Porcel, Laura, Povedano, Mónica, Rubio, Miguel Angel, Gámez, Josep, Cano, Antonio, Paré‐Curell, Martí, Bajo, Lorena, Sotoca, Javier, Clarimón, Jordi, Balasa, Mircea, Antonell, Anna, Lladó, Albert, Sánchez‐Valle, Raquel, Rojas‐García, Ricard, Gelpi, Ellen
Publicado 2021

Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease

por Ximelis, Teresa, Marín-Moreno, Alba, Espinosa, Juan Carlos, Eraña, Hasier, Charco, Jorge M., Hernández, Isabel, Riveira, Carmen, Alcolea, Daniel, González-Roca, Eva, Aldecoa, Iban, Molina-Porcel, Laura, Parchi, Piero, Rossi, Marcello, Castilla, Joaquín, Ruiz-García, Raquel, Gelpi, Ellen, Torres, Juan María, Sánchez-Valle, Raquel
Publicado 2021

Atypical astroglial pTDP‐43 pathology in astroglial predominant tauopathy

por Gelpi, Ellen, Aldecoa, Iban, Lopez‐Villegas, Dolores, Abellan‐Vidal, Maria Teresa, Mercadel‐Fañanas, Pilar, Fortea, Juan, Ribosa, Roser, Morenas, Estrella, Gomez‐Anson, Beatriz, Molina‐Porcel, Laura, Ximelis, Teresa, Borrego, Sergi, Antonell, Anna, Rovelet‐Lecrux, Anne, Klotz, Sigrid, Andres‐Benito, Pol, Sanchez‐Valle, Raquel, Ferrer, Isidre
Publicado 2021

Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease

por Boza-Serrano, Antonio, Vrillon, Agathe, Minta, Karolina, Paulus, Agnes, Camprubí-Ferrer, Lluís, Garcia, Megg, Andreasson, Ulf, Antonell, Anna, Wennström, Malin, Gouras, Gunnar, Dumurgier, Julien, Cognat, Emmanuel, Molina-Porcel, Laura, Balasa, Mircea, Vitorica, Javier, Sánchez-Valle, Raquel, Paquet, Claire, Venero, Jose Luis, Blennow, Kaj, Deierborg, Tomas
Publicado 2022

R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils

por Fan, Ying, Nirujogi, Raja S., Garrido, Alicia, Ruiz-Martínez, Javier, Bergareche-Yarza, Alberto, Mondragón-Rezola, Elisabet, Vinagre-Aragón, Ana, Croitoru, Ioana, Gorostidi Pagola, Ana, Paternain Markinez, Laura, Alcalay, Roy, Hickman, Richard A., Düring, Jonas, Gomes, Sara, Pratuseviciute, Neringa, Padmanabhan, Shalini, Valldeoriola, Francesc, Pérez Sisqués, Leticia, Malagelada, Cristina, Ximelis, Teresa, Molina Porcel, Laura, Martí, Maria José, Tolosa, Eduardo, Alessi, Dario R., Sammler, Esther M.
Publicado 2021

Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease

por Gelpi, Ellen, Baiardi, Simone, Nos, Carlos, Dellavalle, Sofia, Aldecoa, Iban, Ruiz-Garcia, Raquel, Ispierto, Lourdes, Escudero, Domingo, Casado, Virgina, Barranco, Elena, Boltes, Anuncia, Molina-Porcel, Laura, Bargalló, Nuria, Rossi, Marcello, Mammana, Angela, Tiple, Dorina, Vaianella, Luana, Stoegmann, Elisabeth, Simonitsch-Klupp, Ingrid, Kasprian, Gregor, Klotz, Sigrid, Höftberger, Romana, Budka, Herbert, Kovacs, Gabor G., Ferrer, Isidre, Capellari, Sabina, Sanchez-Valle, Raquel, Parchi, Piero
Publicado 2022

Tau deposition patterns are associated with functional connectivity in primary tauopathies

por Franzmeier, Nicolai, Brendel, Matthias, Beyer, Leonie, Slemann, Luna, Kovacs, Gabor G., Arzberger, Thomas, Kurz, Carolin, Respondek, Gesine, Lukic, Milica J., Biel, Davina, Rubinski, Anna, Frontzkowski, Lukas, Hummel, Selina, Müller, Andre, Finze, Anika, Palleis, Carla, Joseph, Emanuel, Weidinger, Endy, Katzdobler, Sabrina, Song, Mengmeng, Biechele, Gloria, Kern, Maike, Scheifele, Maximilian, Rauchmann, Boris-Stephan, Perneczky, Robert, Rullman, Michael, Patt, Marianne, Schildan, Andreas, Barthel, Henryk, Sabri, Osama, Rumpf, Jost J., Schroeter, Matthias L., Classen, Joseph, Villemagne, Victor, Seibyl, John, Stephens, Andrew W., Lee, Edward B., Coughlin, David G., Giese, Armin, Grossman, Murray, McMillan, Corey T., Gelpi, Ellen, Molina-Porcel, Laura, Compta, Yaroslau, van Swieten, John C., Laat, Laura Donker, Troakes, Claire, Al-Sarraj, Safa, Robinson, John L., Xie, Sharon X., Irwin, David J., Roeber, Sigrun, Herms, Jochen, Simons, Mikael, Bartenstein, Peter, Lee, Virginia M., Trojanowski, John Q., Levin, Johannes, Höglinger, Günter, Ewers, Michael
Publicado 2022

Creating the Pick’s disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick’s disease

por Valentino, Rebecca R, Scotton, William J, Roemer, Shanu F, Lashley, Tammaryn, Heckman, Michael G, Shoai, Maryam, Martinez-Carrasco, Alejandro, Tamvaka, Nicole, Walton, Ronald L, Baker, Matthew C, Macpherson, Hannah L, Real, Raquel, Soto-Beasley, Alexandra I, Mok, Kin, Revesz, Tamas, Warner, Thomas T, Jaunmuktane, Zane, Boeve, Bradley F, Christopher, Elizabeth A, DeTure, Michael, Duara, Ranjan, Graff-Radford, Neill R, Josephs, Keith A, Knopman, David S, Koga, Shunsuke, Murray, Melissa E, Lyons, Kelly E, Pahwa, Rajesh, Parisi, Joseph E, Petersen, Ronald C, Whitwell, Jennifer, Grinberg, Lea T, Miller, Bruce, Schlereth, Athena, Seeley, William W, Spina, Salvatore, Grossman, Murray, Irwin, David J, Lee, Edward B, Suh, EunRan, Trojanowski, John Q, Van Deerlin, Vivianna M, Wolk, David A, Connors, Theresa R, Dooley, Patrick M, Frosch, Matthew P, Oakley, Derek H, Aldecoa, Iban, Balasa, Mircea, Gelpi, Ellen, Borrego-Écija, Sergi, de Eugenio Huélamo, Rosa Maria, Gascon-Bayarri, Jordi, Sánchez-Valle, Raquel, Sanz-Cartagena, Pilar, Piñol-Ripoll, Gerard, Molina-Porcel, Laura, Bigio, Eileen H, Flanagan, Margaret E, Gefen, Tamar, Rogalski, Emily J, Weintraub, Sandra, Redding-Ochoa, Javier, Chang, Koping, Troncoso, Juan C, Prokop, Stefan, Newell, Kathy L, Ghetti, Bernardino, Jones, Matthew, Richardson, Anna, Robinson, Andrew C, Roncaroli, Federico, Snowden, Julie, Allinson, Kieren, Green, Oliver, Rowe, James B, Singh, Poonam, Beach, Thomas G, Serrano, Geidy E, Flowers, Xena E, Goldman, James E, Heaps, Allison C, Leskinen, Sandra P, Teich, Andrew F, Black, Sandra E, Keith, Julia L, Masellis, Mario, Bodi, Istvan, King, Andrew, Sarraj, Safa-Al, Troakes, Claire, Halliday, Glenda M, Hodges, John R, Kril, Jillian J, Kwok, John B, Piguet, Olivier, Gearing, Marla, Arzberger, Thomas, Roeber, Sigrun, Attems, Johannes, Morris, Christopher M, Thomas, Alan J, Evers, Bret M., White, Charles L, Mechawar, Naguib, Sieben, Anne A, Cras, Patrick P, De Vil, Bart B, De Deyn, Peter Paul P.P., Duyckaerts, Charles, Le Ber, Isabelle, Seihean, Danielle, Turbant-Leclere, Sabrina, MacKenzie, Ian R, McLean, Catriona, Cykowski, Matthew D, Ervin, John F, Wang, Shih-Hsiu J, Graff, Caroline, Nennesmo, Inger, Nagra, Rashed M, Riehl, James, Kovacs, Gabor G, Giaccone, Giorgio, Nacmias, Benedetta, Neumann, Manuela, Ang, Lee-Cyn, Finger, Elizabeth C, Blauwendraat, Cornelis, Nalls, Mike A, Singleton, Andrew B, Vitale, Dan, Cunha, Cristina, Carvalho, Agostinho, Wszolek, Zbigniew K, Morris, Huw R, Rademakers, Rosa, Hardy, John A, Dickson, Dennis W, Rohrer, Jonathan D, Ross, Owen A
Publicado 2023