Asymmetric trichotomous partitioning overcomes dataset limitations in building machine learning models for predicting siRNA efficacy

por Monopoli, Kathryn R., Korkin, Dmitry, Khvorova, Anastasia
Publicado 2023

Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs

por Shmushkovich, Taisia, Monopoli, Kathryn R, Homsy, Diana, Leyfer, Dmitriy, Betancur-Boissel, Monica, Khvorova, Anastasia, Wolfson, Alexey D
Publicado 2018

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

por Tang, Qi, Fakih, Hassan H., Zain UI Abideen, Mohammad, Hildebrand, Samuel R., Afshari, Khashayar, Gross, Katherine Y., Sousa, Jacquelyn, Maebius, Allison S., Bartholdy, Christina, Søgaard, Pia Pernille, Jackerott, Malene, Hariharan, Vignesh, Summers, Ashley, Fan, Xueli, Okamura, Ken, Monopoli, Kathryn R., Cooper, David A., Echeverria, Dimas, Bramato, Brianna, McHugh, Nicholas, Furgal, Raymond C., Dresser, Karen, Winter, Sarah J., Biscans, Annabelle, Chuprin, Jane, Haddadi, Nazgol-Sadat, Sherman, Shany, Yıldız-Altay, Ümmügülsüm, Rashighi, Mehdi, Richmond, Jillian M., Bouix-Peter, Claire, Blanchard, Carine, Clauss, Adam, Alterman, Julia F., Khvorova, Anastasia, Harris, John E.
Publicado 2023