Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors

por Sartori, Geraldo Rodrigues, Leitão, Andrei, Montanari, Carlos A., Laughton, Charles A.
Publicado 2019

Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

por Lin, Chi-Chuan, Suen, Kin Man, Stainthorp, Amy, Wieteska, Lukasz, Biggs, George S., Leitão, Andrei, Montanari, Carlos A., Ladbury, John E.
Publicado 2019

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

por Batista, Fernanda A. H., Ramos, Sérgio L., Tassone, Giusy, Leitão, Andrei, Montanari, Carlos A., Botta, Maurizio, Mori, Mattia, Borges, Júlio C.
Publicado 2020

Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors

por Burtoloso, Antonio C. B., de Albuquerque, Sérgio, Furber, Mark, Gomes, Juliana C., Gonçalez, Cristiana, Kenny, Peter W., Leitão, Andrei, Montanari, Carlos A., Quilles, José Carlos, Ribeiro, Jean F. R., Rocha, Josmar R.
Publicado 2017

Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay

por Wiggers, Helton J., Rocha, Josmar R., Fernandes, William B., Sesti-Costa, Renata, Carneiro, Zumira A., Cheleski, Juliana, da Silva, Albérico B. F., Juliano, Luiz, Cezari, Maria H. S., Silva, João S., McKerrow, James H., Montanari, Carlos A.
Publicado 2013

Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

por Cianni, Lorenzo, Lemke, Carina, Gilberg, Erik, Feldmann, Christian, Rosini, Fabiana, Rocho, Fernanda dos Reis, Ribeiro, Jean F. R., Tezuka, Daiane Y., Lopes, Carla D., de Albuquerque, Sérgio, Bajorath, Jürgen, Laufer, Stefan, Leitão, Andrei, Gütschow, Michael, Montanari, Carlos A.
Publicado 2020

Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors

por Avelar, Leandro A. A., Camilo, Cristian D., de Albuquerque, Sérgio, Fernandes, William B., Gonçalez, Cristiana, Kenny, Peter W., Leitão, Andrei, McKerrow, James H., Montanari, Carlos A., Orozco, Erika V. Meñaca, Ribeiro, Jean F. R., Rocha, Josmar R., Rosini, Fabiana, Saidel, Marta E.
Publicado 2015