The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

por Marin, Jose JG, Monte, Maria J, Blazquez, Alba G, Macias, Rocio IR, Serrano, Maria A, Briz, Oscar
Publicado 2014

Role of Genetic Variations in the Hepatic Handling of Drugs

por Marin, Jose J. G., Serrano, Maria A., Monte, Maria J., Sanchez-Martin, Anabel, Temprano, Alvaro G., Briz, Oscar, Romero, Marta R.
Publicado 2020

Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland

por Blazquez, Alba M. G., Macias, Rocio I. R., Cives-Losada, Candela, de la Iglesia, Alberto, Marin, Jose J. G., Monte, Maria J.
Publicado 2017

Novel Pharmacological Options in the Treatment of Cholangiocarcinoma: Mechanisms of Resistance

por Marin, Jose J. G., Sanchon-Sanchez, Paula, Cives-Losada, Candela, del Carmen, Sofía, González-Santiago, Jesús M., Monte, Maria J., Macias, Rocio I. R.
Publicado 2021

Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics

por Macias, Rocio I.R., Monte, Maria J., Serrano, Maria A., González-Santiago, Jesús M., Martín-Arribas, Isabel, Simão, André L., Castro, Rui E., González-Gallego, Javier, Mauriz, José L., Marin, Jose J.G.
Publicado 2021

Molecular Bases of Drug Resistance in Hepatocellular Carcinoma

por Marin, Jose J.G., Macias, Rocio I.R., Monte, Maria J., Romero, Marta R., Asensio, Maitane, Sanchez-Martin, Anabel, Cives-Losada, Candela, Temprano, Alvaro G., Espinosa-Escudero, Ricardo, Reviejo, Maria, Bohorquez, Laura H., Briz, Oscar
Publicado 2020

Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis

por Lumbreras, Sara, Ricobaraza, Ana, Baila-Rueda, Lucia, Gonzalez-Aparicio, Manuela, Mora-Jimenez, Lucia, Uriarte, Iker, Bunuales, Maria, Avila, Matias A., Monte, Maria J., Marin, Jose J.G., Cenarro, Ana, Gonzalez-Aseguinolaza, Gloria, Hernandez-Alcoceba, Ruben
Publicado 2021

Cellular Mechanisms Accounting for the Refractoriness of Colorectal Carcinoma to Pharmacological Treatment

por Marin, Jose J.G., Macias, Rocio I.R., Monte, Maria J., Herraez, Elisa, Peleteiro-Vigil, Ana, de Blas, Beatriz Sanchez, Sanchon-Sanchez, Paula, Temprano, Alvaro G., Espinosa-Escudero, Ricardo A., Lozano, Elisa, Briz, Oscar, Romero, Marta R.
Publicado 2020

Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers

por Marin, Jose J. G., Monte, Maria J., Macias, Rocio I. R., Romero, Marta R., Herraez, Elisa, Asensio, Maitane, Ortiz-Rivero, Sara, Cives-Losada, Candela, Di Giacomo, Silvia, Gonzalez-Gallego, Javier, Mauriz, Jose L., Efferth, Thomas, Briz, Oscar
Publicado 2022

Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation

por Alonso-Peña, Marta, Espinosa-Escudero, Ricardo, Hermanns, Heike M., Briz, Oscar, Herranz, Jose M., Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C., Juamperez, Javier, Avila, Matias, Argemi, Josepmaria, Bataller, Ramon, Crespo, Javier, Monte, Maria J., Geier, Andreas, Herraez, Elisa, Marin, Jose J. G.
Publicado 2022

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

por Nuño-Lámbarri, Natalia, Domínguez-Pérez, Mayra, Baulies-Domenech, Anna, Monte, Maria J., Marin, Jose J. G., Rosales-Cruz, Patricia, Souza, Verónica, Miranda, Roxana U., Bucio, Leticia, Montalvo-Jave, Eduardo E., Concepción Gutiérrez-Ruiz, María, García-Ruiz, Carmen, Fernández-Checa, José C., Gomez-Quiroz, Luis Enrique
Publicado 2016

JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma

por Manieri, Elisa, Folgueira, Cintia, Rodríguez, María Elena, Leiva-Vega, Luis, Esteban-Lafuente, Laura, Chen, Chaobo, Cubero, Francisco Javier, Barrett, Tamera, Cavanagh-Kyros, Julie, Seruggia, Davide, Rosell, Alejandro, Sanchez-Cabo, Fátima, Gómez, Manuel Jose, Monte, Maria J., G. Marin, Jose J., Davis, Roger J., Mora, Alfonso, Sabio, Guadalupe
Publicado 2020

Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

por Abu‐Hayyeh, Shadi, Ovadia, Caroline, Lieu, TinaMarie, Jensen, Dane D., Chambers, Jenny, Dixon, Peter H., Lövgren‐Sandblom, Anita, Bolier, Ruth, Tolenaars, Dagmar, Kremer, Andreas E., Syngelaki, Argyro, Noori, Muna, Williams, David, Marin, Jose J.G., Monte, Maria J., Nicolaides, Kypros H., Beuers, Ulrich, Oude‐Elferink, Ronald, Seed, Paul T., Chappell, Lucy, Marschall, Hanns‐Ulrich, Bunnett, Nigel W., Williamson, Catherine
Publicado 2015

Beneficial effect of ursodeoxycholic acid in patients with acyl‐CoA oxidase 2 (ACOX2) deficiency–associated hypertransaminasemia

por Alonso‐Peña, Marta, Espinosa‐Escudero, Ricardo, Herraez, Elisa, Briz, Oscar, Cagigal, Maria Luisa, Gonzalez‐Santiago, Jesus M., Ortega‐Alonso, Aida, Fernandez‐Rodriguez, Conrado, Bujanda, Luis, Calvo Sanchez, Marta, D´Avola, Delia, Londoño, Maria‐Carlota, Diago, Moises, Fernandez‐Checa, Jose C., Garcia‐Ruiz, Carmen, Andrade, Raul J., Lammert, Frank, Prieto, Jesus, Crespo, Javier, Juamperez, Javier, Diaz‐Gonzalez, Alvaro, Monte, Maria J., Marin, Jose J. G.
Publicado 2022

Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury

por Iruzubieta, Paula, Goikoetxea-Usandizaga, Naroa, Barbier-Torres, Lucía, Serrano-Maciá, Marina, Fernández-Ramos, David, Fernández-Tussy, Pablo, Gutiérrez-de-Juan, Virginia, Lachiondo-Ortega, Sofia, Simon, Jorge, Bravo, Miren, Lopitz-Otsoa, Fernando, Robles, Mercedes, Ferre-Aracil, Carlos, Varela-Rey, Marta, Elguezabal, Natalia, Calleja, José Luis, Lu, Shelly C., Milkiewicz, Malgorzata, Milkiewicz, Piotr, Anguita, Juan, Monte, María J., Marin, José J.G., López-Hoyos, Marcos, Delgado, Teresa C., Rincón, Mercedes, Crespo, Javier, Martínez-Chantar, María Luz
Publicado 2021

Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for...

por Grove, Jane I., Stephens, Camilla, Lucena, M. Isabel, Andrade, Raúl J., Weber, Sabine, Gerbes, Alexander, Bjornsson, Einar S., Stirnimann, Guido, Daly, Ann K., Hackl, Matthias, Khamina-Kotisch, Kseniya, Marin, Jose J. G., Monte, Maria J., Paciga, Sara A., Lingaya, Melanie, Forootan, Shiva S., Goldring, Christopher E. P., Poetz, Oliver, Lombaard, Rudolf, Stege, Alexandra, Bjorrnsson, Helgi K., Robles-Diaz, Mercedes, Li, Dingzhou, Tran, Thi Dong Binh, Ramaiah, Shashi K., Samodelov, Sophia L., Kullak-Ublick, Gerd A., Aithal, Guruprasad P.
Publicado 2023

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

por Urman, Jesús M., Herranz, José M., Uriarte, Iker, Rullán, María, Oyón, Daniel, González, Belén, Fernandez-Urién, Ignacio, Carrascosa, Juan, Bolado, Federico, Zabalza, Lucía, Arechederra, María, Alvarez-Sola, Gloria, Colyn, Leticia, Latasa, María U., Puchades-Carrasco, Leonor, Pineda-Lucena, Antonio, Iraburu, María J., Iruarrizaga-Lejarreta, Marta, Alonso, Cristina, Sangro, Bruno, Purroy, Ana, Gil, Isabel, Carmona, Lorena, Cubero, Francisco Javier, Martínez-Chantar, María L., Banales, Jesús M., Romero, Marta R., Macias, Rocio I.R., Monte, Maria J., Marín, Jose J. G., Vila, Juan J., Corrales, Fernando J., Berasain, Carmen, Fernández-Barrena, Maite G., Avila, Matías A.
Publicado 2020