Dissecting genetic risk factors in breast cancer

por Harro, Carly M., Monteiro, Alvaro N.A.
Publicado 2017

Germline Missense Variants in BRCA1: New Trends and Challenges for Clinical Annotation

por Golubeva, Volha A., Nepomuceno, Thales C., Monteiro, Alvaro N. A.
Publicado 2019

DNA damage response and repair in perspective: Aedes aegypti, Drosophila melanogaster and Homo sapiens

por Mota, Maria Beatriz S., Carvalho, Marcelo Alex, Monteiro, Alvaro N. A., Mesquita, Rafael D.
Publicado 2019

Functional Impact of Missense Variants in BRCA1 Predicted by Supervised Learning

por Karchin, Rachel, Monteiro, Alvaro N. A, Tavtigian, Sean V, Carvalho, Marcelo A, Sali, Andrej
Publicado 2007

Yeast two-hybrid junk sequences contain selected linear motifs

por Liu, Yun, Woods, Nicholas T., Kim, Dewey, Sweet, Michael, Monteiro, Alvaro N. A., Karchin, Rachel
Publicado 2011

Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility

por Baskin, Rebekah, Woods, Nicholas T., Mendoza-Fandiño, Gustavo, Forsyth, Peter, Egan, Kathleen M., Monteiro, Alvaro N.A.
Publicado 2015

Mutational heterogeneity in non-serous ovarian cancers

por Teer, Jamie K., Yoder, Sean, Gjyshi, Anxhela, Nicosia, Santo V., Zhang, Chaomei, Monteiro, Alvaro N. A.
Publicado 2017

Effects of long-term norepinephrine treatment on normal immortalized ovarian and fallopian tube cells

por Dash, Sweta, Yoder, Sean, Mesa, Tania, Smith, Andrew, Cen, Ling, Eschrich, Steven, Armaiz-Pena, Guillermo N., Monteiro, Alvaro N. A.
Publicado 2021

Probing Structure-Function Relationships in Missense Variants in the Carboxy-Terminal Region of BRCA1

por Carvalho, Renato S., Abreu, Renata B. V., Velkova, Aneliya, Marsillac, Sylvia, Rodarte, Renato S., Suarez-Kurtz, Guilherme, Iversen, Edwin S., Monteiro, Alvaro N. A., Carvalho, Marcelo A.
Publicado 2014

Early transcriptional response of human ovarian and fallopian tube surface epithelial cells to norepinephrine

por Gjyshi, Anxhela, Dash, Sweta, Cen, Ling, Cheng, Chia-Ho, Zhang, Chaomei, Yoder, Sean J., Teer, Jamie K., Armaiz-Pena, Guillermo N., Monteiro, Alvaro N. A.
Publicado 2018

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI

por Hu, Wen-Feng, Krieger, Kimiko L., Lagundžin, Dragana, Li, Xueli, Cheung, Ronald S., Taniguchi, Toshiyasu, Johnson, Keith R., Bessho, Tadayoshi, Monteiro, Alvaro N. A., Woods, Nicholas T.
Publicado 2019

Functional Restoration of BRCA1 Nonsense Mutations by Aminoglycoside-Induced Readthrough

por Abreu, Renata B. V., Gomes, Thiago T., Nepomuceno, Thales C., Li, Xueli, Fuchshuber-Moraes, Mateus, De Gregoriis, Giuliana, Suarez-Kurtz, Guilherme, Monteiro, Alvaro N. A., Carvalho, Marcelo A.
Publicado 2022

Assessment of small in-frame indels and C-terminal nonsense variants of BRCA1 using a validated functional assay

por Nepomuceno, Thales C., dos Santos, Ana P. P., Fernandes, Vanessa C., Elias, Anna B. R., Gomes, Thiago T., Suarez-Kurtz, Guilherme, Iversen, Edwin S., Couch, Fergus J., Monteiro, Alvaro N. A., Carvalho, Marcelo A.
Publicado 2022

Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins

por Golubeva, Volha A., Nepomuceno, Thales C., de Gregoriis, Giuliana, Mesquita, Rafael D., Li, Xueli, Dash, Sweta, Garcez, Patrícia P., Suarez-Kurtz, Guilherme, Izumi, Victoria, Koomen, John, Carvalho, Marcelo A., Monteiro, Alvaro N. A.
Publicado 2020

Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

por Hart, Steven N., Hoskin, Tanya, Shimelis, Hermela, Moore, Raymond M., Feng, Bingjian, Thomas, Abigail, Lindor, Noralane M., Polley, Eric C., Goldgar, David E., Iversen, Edwin, Monteiro, Alvaro N.A., Suman, Vera J., Couch, Fergus J.
Publicado 2018

A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

por Schell, Michael J., Yang, Mingli, Teer, Jamie K., Lo, Fang Yin, Madan, Anup, Coppola, Domenico, Monteiro, Alvaro N. A., Nebozhyn, Michael V., Yue, Binglin, Loboda, Andrey, Bien-Willner, Gabriel A., Greenawalt, Danielle M., Yeatman, Timothy J.
Publicado 2016

Functional characterization of 84 PALB2 variants of uncertain significance

por Wiltshire, Timothy, Ducy, Mandy, Foo, Tzeh Keong, Hu, Chunling, Lee, Kun Y., Belur Nagaraj, Anil, Rodrigue, Amélie, Gomes, Thiago T., Simard, Jacques, Monteiro, Alvaro N. A., Xia, Bing, Carvalho, Marcelo A., Masson, Jean-Yves, Couch, Fergus J.
Publicado 2019

An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance

por Iversen, Edwin S., Lipton, Gary, Hart, Steven N., Lee, Kun Y., Hu, Chunling, Polley, Eric C., Pesaran, Tina, Yussuf, Amal, LaDuca, Holly, Chao, Elizabeth, Karam, Rachid, Goldgar, David E., Couch, Fergus J., Monteiro, Alvaro N. A.
Publicado 2022

Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance

por Richardson, Marcy E., Hu, Chunling, Lee, Kun Y., LaDuca, Holly, Fulk, Kelly, Durda, Kate M., Deckman, Ashley M., Goldgar, David E., Monteiro, Alvaro N.A., Gnanaolivu, Rohan, Hart, Steven N., Polley, Eric C., Chao, Elizabeth, Pesaran, Tina, Couch, Fergus J.
Publicado 2021

BRCA1 frameshift variants leading to extended incorrect protein C termini

por Nepomuceno, Thales C., Foo, Tzeh Keong, Richardson, Marcy E., Ranola, John Michael O., Weyandt, Jamie, Varga, Matthew J., Alarcon, Amaya, Gutierrez, Diana, von Wachenfeldt, Anna, Eriksson, Daniel, Kim, Raymond, Armel, Susan, Iversen, Edwin, Couch, Fergus J., Borg, Åke, Xia, Bing, Carvalho, Marcelo A., Monteiro, Alvaro N.A.
Publicado 2023