Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex

por Sutherell, Charlotte L., Tallant, Cynthia, Monteiro, Octovia P., Yapp, Clarence, Fuchs, Julian E., Fedorov, Oleg, Siejka, Paulina, Müller, Suzanne, Knapp, Stefan, Brenton, James D., Brennan, Paul E., Ley, Steven V.
Publicado 2016

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2

por Moustakim, Moses, Riedel, Kerstin, Schuller, Marion, Gehring, Andrè P., Monteiro, Octovia P., Martin, Sarah P., Fedorov, Oleg, Heer, Jag, Dixon, Darren J., Elkins, Jonathan M., Knapp, Stefan, Bracher, Franz, Brennan, Paul E.
Publicado 2018

[1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains

por Fedorov, Oleg, Lingard, Hannah, Wells, Chris, Monteiro, Octovia P., Picaud, Sarah, Keates, Tracy, Yapp, Clarence, Philpott, Martin, Martin, Sarah J., Felletar, Ildiko, Marsden, Brian D., Filippakopoulos, Panagis, Müller, Susanne, Knapp, Stefan, Brennan, Paul E.
Publicado 2013

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor**

por Clark, Peter G K, Vieira, Lucas C C, Tallant, Cynthia, Fedorov, Oleg, Singleton, Dean C, Rogers, Catherine M, Monteiro, Octovia P, Bennett, James M, Baronio, Roberta, Müller, Susanne, Daniels, Danette L, Méndez, Jacqui, Knapp, Stefan, Brennan, Paul E, Dixon, Darren J
Publicado 2015

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

por Clark, Peter G. K., Vieira, Lucas C. C., Tallant, Cynthia, Fedorov, Oleg, Singleton, Dean C., Rogers, Catherine M., Monteiro, Octovia P., Bennett, James M., Baronio, Roberta, Müller, Susanne, Daniels, Danette L., Méndez, Jacqui, Knapp, Stefan, Brennan, Paul E., Dixon, Darren J.
Publicado 2015

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

por Hay, Duncan A., Fedorov, Oleg, Martin, Sarah, Singleton, Dean C., Tallant, Cynthia, Wells, Christopher, Picaud, Sarah, Philpott, Martin, Monteiro, Octovia P., Rogers, Catherine M., Conway, Stuart J., Rooney, Timothy P. C., Tumber, Anthony, Yapp, Clarence, Filippakopoulos, Panagis, Bunnage, Mark E., Müller, Susanne, Knapp, Stefan, Schofield, Christopher J., Brennan, Paul E.
Publicado 2014

Discovery of a PCAF Bromodomain Chemical Probe

por Moustakim, Moses, Clark, Peter G. K., Trulli, Laura, Fuentes de Arriba, Angel L., Ehebauer, Matthias T., Chaikuad, Apirat, Murphy, Emma J., Mendez‐Johnson, Jacqui, Daniels, Danette, Hou, Chun‐Feng D., Lin, Yu‐Hui, Walker, John R., Hui, Raymond, Yang, Hongbing, Dorrell, Lucy, Rogers, Catherine M., Monteiro, Octovia P., Fedorov, Oleg, Huber, Kilian V. M., Knapp, Stefan, Heer, Jag, Dixon, Darren J., Brennan, Paul E.
Publicado 2016

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

por Moustakim, Moses, Christott, Thomas, Monteiro, Octovia P., Bennett, James, Giroud, Charline, Ward, Jennifer, Rogers, Catherine M., Smith, Paul, Panagakou, Ioanna, Díaz‐Sáez, Laura, Felce, Suet Ling, Gamble, Vicki, Gileadi, Carina, Halidi, Nadia, Heidenreich, David, Chaikuad, Apirat, Knapp, Stefan, Huber, Kilian V. M., Farnie, Gillian, Heer, Jag, Manevski, Nenad, Poda, Gennady, Al‐awar, Rima, Dixon, Darren J., Brennan, Paul E., Fedorov, Oleg
Publicado 2018