Deep phenotyping for precision medicine in Parkinson's disease

por Schalkamp, Ann-Kathrin, Rahman, Nabila, Monzón-Sandoval, Jimena, Sandor, Cynthia
Publicado 2022

Increased brain size in mammals is associated with size variations in gene families with cell signalling, chemotaxis and immune-related functions

por Castillo-Morales, Atahualpa, Monzón-Sandoval, Jimena, Urrutia, Araxi O., Gutiérrez, Humberto
Publicado 2014

Modular reorganization of the global network of gene regulatory interactions during perinatal human brain development

por Monzón-Sandoval, Jimena, Castillo-Morales, Atahualpa, Urrutia, Araxi O., Gutierrez, Humberto
Publicado 2016

Single-Cell Transcriptomics Reveals Conserved Regulatory Networks in Human and Mouse Interneuron Development

por Keefe, Francesca, Monzón-Sandoval, Jimena, Rosser, Anne E., Webber, Caleb, Li, Meng
Publicado 2023

Emergence of co-expression in gene regulatory networks

por Yin, Wencheng, Mendoza, Luis, Monzon-Sandoval, Jimena, Urrutia, Araxi O., Gutierrez, Humberto
Publicado 2021

Human‐Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons

por Monzón‐Sandoval, Jimena, Poggiolini, Ilaria, Ilmer, Tobias, Wade‐Martins, Richard, Webber, Caleb, Parkkinen, Laura
Publicado 2020

Neocortex expansion is linked to size variations in gene families with chemotaxis, cell–cell signalling and immune response functions in mammals

por Castillo-Morales, Atahualpa, Monzón-Sandoval, Jimena, de Sousa, Alexandra A., Urrutia, Araxi O., Gutierrez, Humberto
Publicado 2016

Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons

por Hedegaard, Anne, Monzón-Sandoval, Jimena, Newey, Sarah E., Whiteley, Emma S., Webber, Caleb, Akerman, Colin J.
Publicado 2020

Modular and coordinated expression of immune system regulatory and signaling components in the developing and adult nervous system

por Monzón-Sandoval, Jimena, Castillo-Morales, Atahualpa, Crampton, Sean, McKelvey, Laura, Nolan, Aoife, O’Keeffe, Gerard, Gutierrez, Humberto
Publicado 2015

A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

por Agarwal, Devika, Sandor, Cynthia, Volpato, Viola, Caffrey, Tara M., Monzón-Sandoval, Jimena, Bowden, Rory, Alegre-Abarrategui, Javier, Wade-Martins, Richard, Webber, Caleb
Publicado 2020

Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

por Monzón-Sandoval, Jimena, Burlacu, Elena, Agarwal, Devika, Handel, Adam E., Wei, Liting, Davis, John, Cowley, Sally A., Cader, M. Zameel, Webber, Caleb
Publicado 2022

Optimization of next‐generation sequencing transcriptome annotation for species lacking sequenced genomes

por Ockendon, Nina F., O'Connell, Lauren A., Bush, Stephen J., Monzón‐Sandoval, Jimena, Barnes, Holly, Székely, Tamás, Hofmann, Hans A., Dorus, Steve, Urrutia, Araxi O.
Publicado 2015

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

por Hall-Roberts, Hazel, Agarwal, Devika, Obst, Juliane, Smith, Thomas B., Monzón-Sandoval, Jimena, Di Daniel, Elena, Webber, Caleb, James, William S., Mead, Emma, Davis, John B., Cowley, Sally A.
Publicado 2020

Transcriptional, Behavioral and Biochemical Profiling in the 3xTg-AD Mouse Model Reveals a Specific Signature of Amyloid Deposition and Functional Decline in Alzheimer’s Disease

por Yin, Wencheng, Cerda-Hernández, Navei, Castillo-Morales, Atahualpa, Ruiz-Tejada-Segura, Mayra L., Monzón-Sandoval, Jimena, Moreno-Castilla, Perla, Pérez-Ortega, Rodrigo, Bermudez-Rattoni, Federico, Urrutia, Araxi O., Gutiérrez, Humberto
Publicado 2020

Combining multiomics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy

por Meijboom, Katharina E., Volpato, Viola, Monzón-Sandoval, Jimena, Hoolachan, Joseph M., Hammond, Suzan M., Abendroth, Frank, de Jong, Olivier G., Hazell, Gareth, Ahlskog, Nina, Wood, Matthew J.A., Webber, Caleb, Bowerman, Melissa
Publicado 2021

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

por Mancuso, Renzo, Fryatt, Gemma, Cleal, Madeleine, Obst, Juliane, Pipi, Elena, Monzón-Sandoval, Jimena, Ribe, Elena, Winchester, Laura, Webber, Caleb, Nevado, Alejo, Jacobs, Tom, Austin, Nigel, Theunis, Clara, Grauwen, Karolien, Daniela Ruiz, Eva, Mudher, Amrit, Vicente-Rodriguez, Marta, Parker, Christine A, Simmons, Camilla, Cash, Diana, Richardson, Jill, Jones, Declan N C, Lovestone, Simon, Gómez-Nicola, Diego, Perry, V Hugh
Publicado 2019