Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner

por Kaul, Roma, Risinger, April L., Mooberry, Susan L.
Publicado 2019

Correction: Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner

por Kaul, Roma, Risinger, April L., Mooberry, Susan L.
Publicado 2020

Synthetic Reactions with Rare Taccalonolides Reveal the Value of C-22,23 Epoxidation for Microtubule Stabilizing Potency

por Peng, Jiangnan, Risinger, April L., Li, Jing, Mooberry, Susan L.
Publicado 2014

Regulation of E-cadherin localization by microtubule targeting agents: rapid promotion of cortical E-cadherin through p130Cas/Src inhibition by eribulin

por Dybdal-Hargreaves, Nicholas F., Risinger, April L., Mooberry, Susan L.
Publicado 2017

Correction: Regulation of E-cadherin localization by microtubule targeting agents: rapid promotion of cortical E-cadherin through p130CAS/Src inhibition by eribulin

por Dybdal-Hargreaves, Nicholas F., Risinger, April L., Mooberry, Susan L.
Publicado 2019

Eribulin and Paclitaxel Differentially Alter Extracellular Vesicles and Their Cargo from Triple-Negative Breast Cancer Cells

por Pederson, Petra J., Liang, Huiyun, Filonov, Daria, Mooberry, Susan L.
Publicado 2021

Eribulin Activates the cGAS-STING Pathway via the Cytoplasmic Accumulation of Mitochondrial DNA

por Fermaintt, Charles S., Takahashi-Ruiz, Leila, Liang, Huiyun, Mooberry, Susan L., Risinger, April L.
Publicado 2021

Cytotoxic Dimeric Epipolythiodiketopiperazines from the Ascomycetous Fungus Preussia typharum

por Du, Lin, Robles, Andrew J., King, Jarrod B., Mooberry, Susan L., Cichewicz, Robert H.
Publicado 2014

429 Eribulin Synergizes with STING Agonists by Enhancing Type 1 Interferon Expression and Improves Antitumor Efficacy as Combination Treatment

por Takahashi-Ruiz, Leila, Fermaintt, Charles S., Wilkinson, Nancy, Chan, Peter Y., Mooberry, Susan L., Risinger, April L.
Publicado 2023

The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation

por Risinger, April L, Riffle, Stephen M, Lopus, Manu, Jordan, Mary A, Wilson, Leslie, Mooberry, Susan L
Publicado 2014

The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models

por Takahashi-Ruiz, Leila, Fermaintt, Charles S., Wilkinson, Nancy J., Chan, Peter Y. W., Mooberry, Susan L., Risinger, April L.
Publicado 2022

Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents

por Islam, Farhana, Doshi, Arpit, Robles, Andrew J., Quadery, Tasdique M., Zhang, Xin, Zhou, Xilin, Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
Publicado 2022

Didemnaketals F and G, New Bioactive Spiroketals from a Red Sea Ascidian Didemnum Species

por Shaala, Lamiaa A., Youssef, Diaa T.A., Ibrahim, Sabrin R.M., Mohamed, Gamal A., Badr, Jihan M., Risinger, April L., Mooberry, Susan L.
Publicado 2014

Janus Compounds, 5-Chloro-N(4)-methyl-N(4)-aryl-9H-pyrimido[4,5-b]indole-2,4-diamines, Cause Both Microtubule Depolymerizing and Stabilizing Effects

por Rohena, Cristina C., Risinger, April L., Devambatla, Ravi Kumar Vyas, Dybdal-Hargreaves, Nicholas F., Kaul, Roma, Choudhary, Shruti, Gangjee, Aleem, Mooberry, Susan L.
Publicado 2016

Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential

por Fermaintt, Charles S., Peramuna, Thilini, Cai, Shengxin, Takahashi-Ruiz, Leila, Essif, Jacob Nathaniel, Grant, Corena V., O’Keefe, Barry R., Mooberry, Susan L., Cichewicz, Robert H., Risinger, April L.
Publicado 2021

Altertoxin II, a Highly Effective and Specific Compound against Ewing Sarcoma

por Robles, Andrew J., Dai, Wentao, Haldar, Saikat, Ma, Hongyan, Anderson, Victoria M., Overacker, Ross D., Risinger, April L., Loesgen, Sandra, Houghton, Peter J., Cichewicz, Robert H., Mooberry, Susan L.
Publicado 2021

Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

por Balaguer, Francisco de Asís, Mühlethaler, Tobias, Estévez-Gallego, Juan, Calvo, Enrique, Giménez-Abián, Juan Francisco, Risinger, April L., Sorensen, Erik J., Vanderwal, Christopher D., Altmann, Karl-Heinz, Mooberry, Susan L., Steinmetz, Michel O., Oliva, María Ángela, Prota, Andrea E., Díaz, J. Fernando
Publicado 2019