SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function

por Zhang, Lingxin, Sarangi, Vivekananda, Ho, Ming-Fen, Moon, Irene, Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2021

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants

por Zhang, Lingxin, Sarangi, Vivekananda, Moon, Irene, Yu, Jia, Liu, Duan, Devarajan, Sandhya, Reid, Joel M., Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard
Publicado 2020

Epigenetic regulation of GABA catabolism in iPSC-derived neurons: The molecular links between FGF21 and histone methylation

por Ho, Ming-Fen, Zhang, Cheng, Moon, Irene, Biernacka, Joanna, Coombes, Brandon, Ngo, Quyen, Skillon, Cedric, Skime, Michelle, Oesterle, Tyler, Croarkin, Paul E., Karpyak, Victor M., Li, Hu, Weinshilboum, Richard M.
Publicado 2023

Contribution of FKBP5 Genetic Variation to Gemcitabine Treatment and Survival in Pancreatic Adenocarcinoma

por Ellsworth, Katarzyna A., Eckloff, Bruce W., Li, Liang, Moon, Irene, Fridley, Brooke L., Jenkins, Gregory D., Carlson, Erin, Brisbin, Abra, Abo, Ryan, Bamlet, William, Petersen, Gloria, Wieben, Eric D., Wang, Liewei
Publicado 2013

TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response

por Ho, Ming-Fen, Zhang, Cheng, Zhang, Lingxin, Wei, Lixuan, Zhou, Ying, Moon, Irene, Geske, Jennifer R., Choi, Doo-Sup, Biernacka, Joanna, Frye, Mark, Wen, Zhexing, Karpyak, Victor M., Li, Hu, Weinshilboum, Richard
Publicado 2020

ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants

por Zhang, Lingxin, Sarangi, Vivekananda, Liu, Duan, Ho, Ming-Fen, Grassi, Angela R, Wei, Lixuan, Moon, Irene, Vierkant, Robert A, Larson, Nicholas B, Lazaridis, Konstantinos N, Athreya, Arjun P, Wang, Liewei, Weinshilboum, Richard
Publicado 2022

Plasma TNFSF10 levels associated with acamprosate treatment response in patients with alcohol use disorder

por Ho, Ming-Fen, Zhang, Cheng, Moon, Irene, Coombes, Brandon J., Biernacka, Joanna, Skime, Michelle, Choi, Doo-Sup, Croarkin, Paul E., Frye, Mark A., Ngo, Quyen, Skillon, Cedric, Oesterle, Tyler S., Karpyak, Victor M., Li, Hu, Weinshilboum, Richard M.
Publicado 2022

Genetic variants associated with acamprosate treatment response in alcohol use disorder patients: A multiple omics study

por Ho, Ming‐Fen, Zhang, Cheng, Wei, Lixuan, Zhang, Lingxin, Moon, Irene, Geske, Jennifer R., Skime, Michelle K., Choi, Doo‐Sup, Biernacka, Joanna M., Oesterle, Tyler S., Frye, Mark A., Seppala, Marvin D., Karpyak, Victor M., Li, Hu, Weinshilboum, Richard M.
Publicado 2022

Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism

por Ho, Ming-Fen, Zhang, Cheng, Moon, Irene, Wei, Lixuan, Coombes, Brandon, Biernacka, Joanna, Skime, Michelle, Choi, Doo-Sup, Frye, Mark, Schmidt, Kristen, Gliske, Kate, Braughton, Jacqueline, Ngo, Quyen, Skillon, Cedric, Seppala, Marvin, Oesterle, Tyler, Karpyak, Victor, Li, Hu, Weinshilboum, Richard
Publicado 2022