Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study

por Moons, Rani, van der Wekken-de Bruijne, Renate, Maudsley, Stuart, Lemière, Filip, Lambeir, Anne-Marie, Sobott, Frank
Publicado 2020

Metal ions shape α-synuclein

por Moons, Rani, Konijnenberg, Albert, Mensch, Carl, Van Elzen, Roos, Johannessen, Christian, Maudsley, Stuart, Lambeir, Anne-Marie, Sobott, Frank
Publicado 2020

A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity

por Kumar, Senthil T., Mahul-Mellier, Anne-Laure, Hegde, Ramanath Narayana, Rivière, Gwladys, Moons, Rani, Ibáñez de Opakua, Alain, Magalhães, Pedro, Rostami, Iman, Donzelli, Sonia, Sobott, Frank, Zweckstetter, Markus, Lashuel, Hilal A.
Publicado 2022

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity

por Stephens, Amberley D., Zacharopoulou, Maria, Moons, Rani, Fusco, Giuliana, Seetaloo, Neeleema, Chiki, Anass, Woodhams, Philippa J., Mela, Ioanna, Lashuel, Hilal A., Phillips, Jonathan J., De Simone, Alfonso, Sobott, Frank, Schierle, Gabriele S. Kaminski
Publicado 2020

Decreased Water Mobility Contributes To Increased α‐Synuclein Aggregation

por Stephens, Amberley D., Kölbel, Johanna, Moons, Rani, Chung, Chyi Wei, Ruggiero, Michael T., Mahmoudi, Najet, Shmool, Talia A., McCoy, Thomas M., Nietlispach, Daniel, Routh, Alexander F., Sobott, Frank, Zeitler, J. Axel, Kaminski Schierle, Gabriele S.
Publicado 2023

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity

por Daniels, Malcolm J., Nourse, J. Brucker, Kim, Hanna, Sainati, Valerio, Schiavina, Marco, Murrali, Maria Grazia, Pan, Buyan, Ferrie, John J., Haney, Conor M., Moons, Rani, Gould, Neal S., Natalello, Antonino, Grandori, Rita, Sobott, Frank, Petersson, E. James, Rhoades, Elizabeth, Pierattelli, Roberta, Felli, Isabella, Uversky, Vladimir N., Caldwell, Kim A., Caldwell, Guy A., Krol, Edward S., Ischiropoulos, Harry
Publicado 2019