Role of Angiotensin II in Cardiovascular Diseases: Introducing Bisartans as a Novel Therapy for Coronavirus 2019

por Swiderski, Jordan, Gadanec, Laura Kate, Apostolopoulos, Vasso, Moore, Graham J., Kelaidonis, Konstantinos, Matsoukas, John M., Zulli, Anthony
Publicado 2023

Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19

por Moore, Graham J., Pires, Jose M., Kelaidonis, Konstantinos, Gadanec, Laura Kate, Zulli, Anthony, Apostolopoulos, Vasso, Matsoukas, John M.
Publicado 2021

Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in...

por Moore, Graham J., Ridgway, Harry, Kelaidonis, Konstantinos, Chasapis, Christos T., Ligielli, Irene, Mavromoustakos, Thomas, Bojarska, Joanna, Matsoukas, John M.
Publicado 2022

Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 Therapy

por Ridgway, Harry, Chasapis, Christos T., Kelaidonis, Konstantinos, Ligielli, Irene, Moore, Graham J., Gadanec, Laura Kate, Zulli, Anthony, Apostolopoulos, Vasso, Mavromoustakos, Thomas, Matsoukas, John M.
Publicado 2022

Network-Based Prediction of Side Effects of Repurposed Antihypertensive Sartans against COVID-19 via Proteome and Drug-Target Interactomes

por Kiouri, Despoina P., Ntallis, Charalampos, Kelaidonis, Konstantinos, Peana, Massimiliano, Tsiodras, Sotirios, Mavromoustakos, Thomas, Giuliani, Alessandro, Ridgway, Harry, Moore, Graham J., Matsoukas, John M., Chasapis, Christos T.
Publicado 2023

W254 in furin functions as a molecular gate promoting anti-viral drug binding: Elucidation of putative drug tunneling and docking by non-equilibrium molecular dynamics

por Ridgway, Harry, Orbell, John D., Matsoukas, Minos-Timotheos, Kelaidonis, Konstantinos, Moore, Graham J., Tsiodras, Sotiris, Gorgoulis, Vasilis G., Chasapis, Christos T., Apostolopoulos, Vasso, Matsoukas, John M.
Publicado 2023

Computational and Enzymatic Studies of Sartans in SARS-CoV-2 Spike RBD-ACE2 Binding: The Role of Tetrazole and Perspectives as Antihypertensive and COVID-19 Therapeutics

por Kelaidonis, Konstantinos, Ligielli, Irene, Letsios, Spiros, Vidali, Veroniki P., Mavromoustakos, Thomas, Vassilaki, Niki, Moore, Graham J., Hoffmann, Weronika, Węgrzyn, Katarzyna, Ridgway, Harry, Chasapis, Christos T., Matsoukas, John M.
Publicado 2023

Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2

por Ridgway, Harry, Moore, Graham J., Mavromoustakos, Thomas, Tsiodras, Sotirios, Ligielli, Irene, Kelaidonis, Konstantinos, Chasapis, Christos T., Gadanec, Laura Kate, Zulli, Anthony, Apostolopoulos, Vasso, Petty, Russell, Karakasiliotis, Ioannis, Gorgoulis, Vassilis G., Matsoukas, John M.
Publicado 2022