Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide after Single and Multiple Ascending Oral Doses in Healthy Adult Subjects

por Eckburg, Paul B., Jain, Akash, Walpole, Susannah, Moore, Grayson, Utley, Luke, Manyak, Erika, Dane, Aaron, Melnick, David
Publicado 2019

1288. Phase 1 First-in-Human Single- and Multiple-Ascending Dose Trial Demonstrates Pharmacokinetics (PK) and Tolerability of SPR720, an Oral DNA GyrB Inhibitor for Mycobacterial I...

por Talley, Angela, Thurston, Archie, Moore, Grayson, Satterfield, Myriah M, Manyak, Erika L, Kumar, Vipul, Stokes, Suzanne, Dane, Aaron, Melnick, David
Publicado 2020

First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections

por Talley, Angela K., Thurston, Archie, Moore, Grayson, Gupta, Vipul K., Satterfield, Myriah, Manyak, Erika, Stokes, Suzanne, Dane, Aaron, Melnick, David
Publicado 2021