Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

por Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2020

Mitochondrial oxidative phosphorylation in cutaneous melanoma

por Kumar, Prakrit R., Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A., Moncrieff, Marc D.
Publicado 2020

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

por Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M, Rushworth, Stuart A
Publicado 2021

Modelling Metabolic Shifts during Cardiomyocyte Differentiation, Iron Deficiency and Transferrin Rescue Using Human Pluripotent Stem Cells

por Johnson, Benjamin B., Reinhold, Johannes, Holmes, Terri L., Moore, Jamie A., Cowell, Verity, Bernardo, Andreia S., Rushworth, Stuart A., Vassiliou, Vassilios, Smith, James G. W.
Publicado 2021

Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection

por Mistry, Jayna J., Hellmich, Charlotte, Moore, Jamie A., Jibril, Aisha, Macaulay, Iain, Moreno-Gonzalez, Mar, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2021

PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma

por Kumar, Prakrit R., Saad, Mona, Hellmich, Charlotte, Mistry, Jayna J., Moore, Jamie A., Conway, Shannon, Morris, Christopher J., Bowles, Kristian M., Moncrieff, Marc D., Rushworth, Stuart A.
Publicado 2022

p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors

por Hellmich, Charlotte, Wojtowicz, Edyta, Moore, Jamie A., Mistry, Jayna J., Jibril, Aisha, Johnson, Benjamin B., Smith, James G. W., Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Daratumumab inhibits acute myeloid leukemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells

por Mistry, Jayna J., Moore, Jamie A., Kumar, Prakrit, Marlein, Christopher R., Hellmich, Charlotte, Pillinger, Genevra, Jibril, Aisha, Di Palma, Federica, Collins, Angela, Bowles, Kristian M., Rushworth, Stuart A
Publicado 2020

LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation

por Moore, Jamie A., Mistry, Jayna J., Hellmich, Charlotte, Horton, Rebecca H., Wojtowicz, Edyta E., Jibril, Aisha, Jefferson, Matthew, Wileman, Thomas, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection

por Mistry, Jayna J., Marlein, Christopher R., Moore, Jamie A., Hellmich, Charlotte, Wojtowicz, Edyta E., Smith, James G. W., Macaulay, Iain, Sun, Yu, Morfakis, Adam, Patterson, Angela, Horton, Rebecca H., Divekar, Devina, Morris, Christopher J., Haestier, Anna, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2019