Cryo-EM of kinesin-binding protein: challenges and opportunities from protein-surface interactions

por Atherton, Joseph, Moores, Carolyn A.
Publicado 2021

The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability

por Manka, Szymon W., Moores, Carolyn A.
Publicado 2018

Microtubule structure by cryo-EM: snapshots of dynamic instability

por Manka, Szymon W., Moores, Carolyn A.
Publicado 2018

Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules

por von Loeffelholz, Ottilie, Moores, Carolyn Ann
Publicado 2019

Pseudo‐repeats in doublecortin make distinct mechanistic contributions to microtubule regulation

por Manka, Szymon W, Moores, Carolyn A
Publicado 2020

Delineation of the TRAK binding regions of the kinesin-1 motor proteins

por Randall, Thomas S., Moores, Carolyn, Stephenson, F. Anne
Publicado 2013

Microtubule architecture in vitro and in cells revealed by cryo-electron tomography

por Atherton, Joseph, Stouffer, Melissa, Francis, Fiona, Moores, Carolyn A.
Publicado 2018

Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography

por Atherton, Joseph, Stouffer, Melissa, Francis, Fiona, Moores, Carolyn A.
Publicado 2022

Regulation of KinI kinesin ATPase activity by binding to the microtubule lattice

por Moores, Carolyn A., Hekmat-Nejad, Mohammad, Sakowicz, Roman, Milligan, Ronald A.
Publicado 2003

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

por Peña, Alejandro, Sweeney, Aaron, Cook, Alexander D., Topf, Maya, Moores, Carolyn A.
Publicado 2020

EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends

por Maurer, Sebastian P., Fourniol, Franck J., Bohner, Gergő, Moores, Carolyn A., Surrey, Thomas
Publicado 2012

Tubulin isoform composition tunes microtubule dynamics

por Vemu, Annapurna, Atherton, Joseph, Spector, Jeffrey O., Moores, Carolyn A., Roll-Mecak, Antonina
Publicado 2017

Cryo-EM Structure (4.5-Å) of Yeast Kinesin-5–Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance

por von Loeffelholz, Ottilie, Peña, Alejandro, Drummond, Douglas Robert, Cross, Robert, Moores, Carolyn Ann
Publicado 2019

A microtubule RELION-based pipeline for cryo-EM image processing

por Cook, Alexander D., Manka, Szymon W., Wang, Su, Moores, Carolyn A., Atherton, Joseph
Publicado 2020

Corrigendum to “Cryo-EM Structure (4.5 Å) of Yeast Kinesin-5–Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance” [J. Mol. Biol. 431 (2019) 86...

por von Loeffelholz, Ottilie, Peña, Alejandro, Drummond, Douglas Robert, Cross, Robert, Moores, Carolyn Ann
Publicado 2020

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

por Peña, Alejandro, Sweeney, Aaron, Cook, Alexander D., Locke, Julia, Topf, Maya, Moores, Carolyn A.
Publicado 2021

Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin

por Vemu, Annapurna, Atherton, Joseph, Spector, Jeffrey O., Szyk, Agnieszka, Moores, Carolyn A., Roll-Mecak, Antonina
Publicado 2016

Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites

por Zeeshan, Mohammad, Brady, Declan, Stanway, Rebecca R., Moores, Carolyn A., Holder, Anthony A., Tewari, Rita
Publicado 2020

Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition

por Cook, Alexander D., Roberts, Anthony J., Atherton, Joseph, Tewari, Rita, Topf, Maya, Moores, Carolyn A.
Publicado 2021

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

por Atherton, Joseph, Farabella, Irene, Yu, I-Mei, Rosenfeld, Steven S, Houdusse, Anne, Topf, Maya, Moores, Carolyn A
Publicado 2014