Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients

por Doorn, Karlijn J, Moors, Tim, Drukarch, Benjamin, van de Berg, Wilma DJ, Lucassen, Paul J, van Dam, Anne-Marie
Publicado 2014

Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

por Moors, Tim E., Hoozemans, Jeroen J. M., Ingrassia, Angela, Beccari, Tommaso, Parnetti, Lucilla, Chartier-Harlin, Marie-Christine, van de Berg, Wilma D. J.
Publicado 2017

Wild-type GBA1 increases the α-synuclein tetramer–monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice

por Glajch, Kelly E., Moors, Tim E., Chen, Yi, Bechade, Pascal A., Nam, Alice Y., Rajsombath, Molly M., McCaffery, Thomas D., Dettmer, Ulf, Weihofen, Andreas, Hirst, Warren D., Selkoe, Dennis J., Nuber, Silke
Publicado 2021

Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

por Moors, Tim E., Paciotti, Silvia, Ingrassia, Angela, Quadri, Marialuisa, Breedveld, Guido, Tasegian, Anna, Chiasserini, Davide, Eusebi, Paolo, Duran-Pacheco, Gonzalo, Kremer, Thomas, Calabresi, Paolo, Bonifati, Vincenzo, Parnetti, Lucilla, Beccari, Tommaso, van de Berg, Wilma D. J.
Publicado 2018

Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies

por Moors, Tim E., Mona, Daniel, Luehe, Stefan, Duran-Pacheco, Gonzalo, Spycher, Liz, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N., Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Dernick, Gregor, van de Berg, Wilma D. J., Britschgi, Markus
Publicado 2022

Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson’s Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography

por Tran, Hung Tri, Tsai, Esther H. R., Lewis, Amanda J., Moors, Tim, Bol, J. G. J. M., Rostami, Iman, Diaz, Ana, Jonker, Allert J., Guizar-Sicairos, Manuel, Raabe, Joerg, Stahlberg, Henning, van de Berg, Wilma D. J., Holler, Mirko, Shahmoradian, Sarah H.
Publicado 2020

The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy

por Moors, Tim E., Maat, Christina A., Niedieker, Daniel, Mona, Daniel, Petersen, Dennis, Timmermans-Huisman, Evelien, Kole, Jeroen, El-Mashtoly, Samir F., Spycher, Liz, Zago, Wagner, Barbour, Robin, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N., Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Geurts, Jeroen J. G., Gerwert, Klaus, Britschgi, Markus, van de Berg, Wilma D. J.
Publicado 2021

Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity

por Ramalingam, Nagendran, Jin, Shan-Xue, Moors, Tim E., Fonseca-Ornelas, Luis, Shimanaka, Kazuma, Lei, Shi, Cam, Hugh P., Watson, Aurelia Hays, Brontesi, Lisa, Ding, Lai, Hacibaloglu, Dinc Yasat, Jiang, Haiyang, Choi, Se Joon, Kanter, Ellen, Liu, Lei, Bartels, Tim, Nuber, Silke, Sulzer, David, Mosharov, Eugene V., Chen, Weisheng V., Li, Shaomin, Selkoe, Dennis J., Dettmer, Ulf
Publicado 2023