MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

por Calvo, Sarah E., Clauser, Karl R., Mootha, Vamsi K.
Publicado 2016

MCU encodes the pore conducting mitochondrial calcium currents

por Chaudhuri, Dipayan, Sancak, Yasemin, Mootha, Vamsi K, Clapham, David E
Publicado 2013

On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models

por Walker, Melissa A., Miranda, Maria, Allred, Amanda, Mootha, Vamsi K.
Publicado 2022

Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics

por Flicker, Daniel, Sancak, Yasemin, Mick, Eran, Goldberger, Olga, Mootha, Vamsi K.
Publicado 2019

A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells

por Cracan, Valentin, Titov, Denis V., Shen, Hongying, Grabarek, Zenon, Mootha, Vamsi K.
Publicado 2017

A genetically encoded system for oxygen generation in living cells

por Markhard, Andrew L., McCoy, Jason G., To, Tsz-Leung, Mootha, Vamsi K.
Publicado 2022

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

por Segrè, Ayellet V., Groop, Leif, Mootha, Vamsi K., Daly, Mark J., Altshuler, David
Publicado 2010

CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets

por Li, Yang, Jourdain, Alexis A., Calvo, Sarah E., Liu, Jun S., Mootha, Vamsi K.
Publicado 2017

Human genetic analyses of organelles highlight the nucleus in age-related trait heritability

por Gupta, Rahul, Karczewski, Konrad J, Howrigan, Daniel, Neale, Benjamin M, Mootha, Vamsi K
Publicado 2021

Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia

por Ast, Tslil, Wang, Hong, Marutani, Eizo, Nagashima, Fumiaki, Malhotra, Rajeev, Ichinose, Fumito, Mootha, Vamsi K
Publicado 2023

Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells

por Joshi, Pallavi R., Sadre, Shayan, Guo, Xiaoyan A., McCoy, Jason G., Mootha, Vamsi K.
Publicado 2023

Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell

por Mick, Eran, Titov, Denis V, Skinner, Owen S, Sharma, Rohit, Jourdain, Alexis A, Mootha, Vamsi K
Publicado 2020

A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

por Baughman, Joshua M., Nilsson, Roland, Gohil, Vishal M., Arlow, Daniel H., Gauhar, Zareen, Mootha, Vamsi K.
Publicado 2009

Correction: A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

por Baughman, Joshua M., Nilsson, Roland, Gohil, Vishal M., Arlow, Daniel H., Gauhar, Zareen, Mootha, Vamsi K.
Publicado 2010

Mitochondrial and Nuclear Genomic Responses to Loss of LRPPRC Expression

por Gohil, Vishal M., Nilsson, Roland, Belcher-Timme, Casey A., Luo, Biao, Root, David E., Mootha, Vamsi K.
Publicado 2010

Structural insights into the Ca(2+)-dependent gating of the human mitochondrial calcium uniporter

por Wang, Yan, Han, Yan, She, Ji, Nguyen, Nam X, Mootha, Vamsi K, Bai, Xiao-chen, Jiang, Youxing
Publicado 2020

CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA

por Mok, Beverly Y., Kotrys, Anna V., Raguram, Aditya, Huang, Tony P., Mootha, Vamsi K., Liu, David R.
Publicado 2022

An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

por Ghosh, Sagnika, Basu Ball, Writoban, Madaris, Travis R., Srikantan, Subramanya, Madesh, Muniswamy, Mootha, Vamsi K., Gohil, Vishal M.
Publicado 2020

Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU

por MacEwen, Melissa JS, Markhard, Andrew L, Bozbeyoglu, Mert, Bradford, Forrest, Goldberger, Olga, Mootha, Vamsi K, Sancak, Yasemin
Publicado 2020

MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake

por Perocchi, Fabiana, Gohil, Vishal M., Girgis, Hany S., Bao, X. Robert, McCombs, Janet E., Palmer, Amy E., Mootha, Vamsi K.
Publicado 2010