Leflunomide Synergizes with Gemcitabine in Growth Inhibition of PC Cells and Impairs c-Myc Signaling through PIM Kinase Targeting

por Buettner, Ralf, Morales, Corey, Wu, Xiwei, Sanchez, James F., Li, Hongzhi, Melstrom, Laleh G., Rosen, Steven T.
Publicado 2019

Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine

por Buettner, Ralf, Nguyen, Le Xuan Truong, Morales, Corey, Chen, Min-Hsuan, Wu, Xiwei, Chen, Lisa S., Hoang, Dinh Hoa, Hernandez Vargas, Servando, Pullarkat, Vinod, Gandhi, Varsha, Marcucci, Guido, Rosen, Steven T.
Publicado 2021

Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer

por Phan, Thuy, Nguyen, Vu H., Buettner, Ralf, Morales, Corey, Yang, Lifeng, Wong, Paul, Tsai, Weiman, Salazar, Marcela d'Alincourt, Gil, Ziv, Diamond, Don J, Rabinowitz, Joshua D., Rosen, Steven, Melstrom, Laleh G.
Publicado 2021

Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism

por Hoang, Dinh Hoa, Morales, Corey, Rodriguez, Ivan Rodriguez, Valerio, Melissa, Guo, Jiamin, Chen, Min-Hsuan, Wu, Xiwei, Horne, David, Gandhi, Varsha, Chen, Lisa S., Zhang, Bin, Pullarkat, Vinod, Rosen, Steven T., Marcucci, Guido, Buettner, Ralf, Nguyen, Le Xuan Truong
Publicado 2022