Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic

por Moreno, Pedro M. D., Pêgo, Ana P.
Publicado 2014

Engineering a Novel Self-Assembled Multi-siRNA Nanocaged Architecture with Controlled Enzyme-Mediated siRNA Release

por Moreno, Pedro M. D., Cortinhas, João, Martins, Ana S., Pêgo, Ana P.
Publicado 2022

Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene

por Kralovicova, Jana, Moreno, Pedro M.D., Cross, Nicholas C.P., Pêgo, Ana Paula, Vorechovsky, Igor
Publicado 2016

A synthetic snRNA m(3)G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids

por Moreno, Pedro M. D., Wenska, Malgorzata, Lundin, Karin E., Wrange, Örjan, Strömberg, Roger, Smith, C. I. Edvard
Publicado 2009

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression

por Oprea, Iulian I, Viola, Joana R, Moreno, Pedro M D, Simonson, Oscar E, Rodin, Sergey, Teller, Nathalie, Tryggvason, Karl, Lundin, Karin E, Girnita, Leonard, Smith, Carl Inge Edvard
Publicado 2014

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression

por Zaghloul, Eman M., Gissberg, Olof, Moreno, Pedro M.D., Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S., Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E., Smith, C.I. Edvard
Publicado 2017

Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury

por Moreno, Pedro M.D., Ferreira, Ana R., Salvador, Daniela, Rodrigues, Maria T., Torrado, Marília, Carvalho, Eva D., Tedebark, Ulf, Sousa, Mónica M., Amaral, Isabel F., Wengel, Jesper, Pêgo, Ana P.
Publicado 2018

Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA

por Zaghloul, Eman M., Madsen, Andreas S., Moreno, Pedro M. D., Oprea, Iulian I., El-Andaloussi, Samir, Bestas, Burcu, Gupta, Pankaj, Pedersen, Erik B., Lundin, Karin E., Wengel, Jesper, Smith, C. I. Edvard
Publicado 2011

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

por Moreno, Pedro M. D., Geny, Sylvain, Pabon, Y. Vladimir, Bergquist, Helen, Zaghloul, Eman M., Rocha, Cristina S. J., Oprea, Iulian I., Bestas, Burcu, Andaloussi, Samir EL, Jørgensen, Per T., Pedersen, Erik B., Lundin, Karin E., Zain, Rula, Wengel, Jesper, Smith, C. I. Edvard
Publicado 2013

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

por Ezzat, Kariem, EL Andaloussi, Samir, Zaghloul, Eman M., Lehto, Taavi, Lindberg, Staffan, Moreno, Pedro M. D., Viola, Joana R., Magdy, Tarek, Abdo, Rania, Guterstam, Peter, Sillard, Rannar, Hammond, Suzan M., Wood, Matthew J. A., Arzumanov, Andrey A., Gait, Michael J., Smith, C. I. Edvard, Hällbrink, Mattias, Langel, Ülo
Publicado 2011

Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

por Geny, Sylvain, Moreno, Pedro M. D., Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K., Isse, Abdirisaq J., El-Madani, Amro M., Lou, Chenguang, Pabon, Y. Vladimir, Anderson, Brooke A., Zaghloul, Eman M., Zain, Rula, Hrdlicka, Patrick J., Jørgensen, Per T., Nilsson, Mats, Lundin, Karin E., Pedersen, Erik B., Wengel, Jesper, Smith, C. I. Edvard
Publicado 2016

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

por EL Andaloussi, Samir, Lehto, Taavi, Mäger, Imre, Rosenthal-Aizman, Katri, Oprea, Iulian I., Simonson, Oscar E., Sork, Helena, Ezzat, Kariem, Copolovici, Dana M., Kurrikoff, Kaido, Viola, Joana R., Zaghloul, Eman M., Sillard, Rannar, Johansson, Henrik J., Said Hassane, Fatouma, Guterstam, Peter, Suhorutšenko, Julia, Moreno, Pedro M. D., Oskolkov, Nikita, Hälldin, Jonas, Tedebark, Ulf, Metspalu, Andres, Lebleu, Bernard, Lehtiö, Janne, Smith, C. I. Edvard, Langel, Ülo
Publicado 2011