An integrated modelling approach for targeted degradation: insights on optimization, data requirements and PKPD predictions from semi- or fully-mechanistic models and exact steady...

por Guzzetti, Sofia, Morentin Gutierrez, Pablo
Publicado 2023

Evolving data analysis of an Oral Lipid Tolerance Test toward the standard for the Oral Glucose Tolerance Test: Cross species modeling effects of AZD7687 on plasma triacylglycerol

por Morentin Gutierrez, Pablo, Yates, James, Nilsson, Catarina, Birtles, Sue
Publicado 2019

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER(+) Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance

por Lawson, Mandy, Cureton, Natalie, Ros, Susana, Cheraghchi-Bashi, Azadeh, Urosevic, Jelena, D'Arcy, Sophie, Delpuech, Oona, DuPont, Michelle, Fisher, David I., Gangl, Eric T., Lewis, Hilary, Trueman, Dawn, Wali, Neha, Williamson, Stuart C., Moss, Jennifer, Montaudon, Elodie, Derrien, Heloise, Marangoni, Elisabetta, Miragaia, Ricardo J., Gagrica, Sladjana, Morentin-Gutierrez, Pablo, Moss, Thomas A., Maglennon, Gareth, Sutton, Daniel, Polanski, Radoslaw, Rosen, Alan, Cairns, Jonathan, Zhang, Pei, Sánchez-Guixé, Mònica, Serra, Violeta, Critchlow, Susan E., Scott, James S., Lindemann, Justin P.O., Barry, Simon T., Klinowska, Teresa, Morrow, Christopher J., S Carnevalli, Larissa
Publicado 2023