A Membrane-bound eIF2 Alpha Kinase Located in Endosomes Is Regulated by Heme and Controls Differentiation and ROS Levels in Trypanosoma cruzi

por da Silva Augusto, Leonardo, Moretti, Nilmar Silvio, Ramos, Thiago Cesar Prata, de Jesus, Teresa Cristina Leandro, Zhang, Min, Castilho, Beatriz A., Schenkman, Sergio
Publicado 2015

Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress

por do Monte, Rubens Lima, Moreira, Paulo Otávio Lourenço, de Sousa, Alessandra Mara, Garcia, Miguel Antonio do Nascimento, Maran, Suellen Rodrigues, Moretti, Nilmar Silvio
Publicado 2022

Mitochondrial Sirtuin TcSir2rp3 Affects TcSODA Activity and Oxidative Stress Response in Trypanosoma cruzi

por dos Santos Moura, Leila, Santana Nunes, Vinícius, Gomes, Antoniel A. S., Sousa, Ana Caroline de Castro Nascimento, Fontes, Marcos R. M., Schenkman, Sergio, Moretti, Nilmar Silvio
Publicado 2021

Chemical Constituents of Anacardium occidentale as Inhibitors of Trypanosoma cruzi Sirtuins

por Matutino Bastos, Tanira, Mannochio Russo, Helena, Silvio Moretti, Nilmar, Schenkman, Sergio, Marcourt, Laurence, Gupta, Mahabir Prashad, Wolfender, Jean-Luc, Ferreira Queiroz, Emerson, Botelho Pereira Soares, Milena
Publicado 2019

Trypanin Disruption Affects the Motility and Infectivity of the Protozoan Trypanosoma cruzi

por Saenz-Garcia, Jose L., Borges, Beatriz S., Souza-Melo, Normanda, Machado, Luiz V., Miranda, Juliana S., Pacheco-Lugo, Lisandro Alfonso, Moretti, Nilmar S., Wheleer, Richard, Soares Medeiros, Lia C., DaRocha, Wanderson D.
Publicado 2022

Extracellular Vesicles From Sporothrix brasiliensis Are an Important Virulence Factor That Induce an Increase in Fungal Burden in Experimental Sporotrichosis

por Ikeda, Marcelo Augusto Kazuo, de Almeida, José Roberto Fogaça, Jannuzzi, Grasielle Pereira, Cronemberger-Andrade, André, Torrecilhas, Ana Cláudia Trocoli, Moretti, Nilmar Silvio, da Cunha, Julia Pinheiro Chagas, de Almeida, Sandro Rogério, Ferreira, Karen Spadari
Publicado 2018

Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes

por Matutino Bastos, Tanira, Botelho Pereira Soares, Milena, Haddad Franco, Caio, Alcântara, Laura, Antonini, Lorenzo, Sabatino, Manuela, Mautone, Nicola, Holanda Freitas-Junior, Lucio, Moraes, Carolina Borsoi, Ragno, Rino, Rotili, Dante, Schenkman, Sergio, Mai, Antonello, Silvio Moretti, Nilmar
Publicado 2020

Toxoplasma gondii Chitinase Induces Macrophage Activation

por Almeida, Fausto, Sardinha-Silva, Aline, da Silva, Thiago Aparecido, Pessoni, André Moreira, Pinzan, Camila Figueiredo, Alegre-Maller, Ana Claudia Paiva, Cecílio, Nerry Tatiana, Moretti, Nilmar Silvio, Damásio, André Ricardo Lima, Pedersoli, Wellington Ramos, Mineo, José Roberto, Silva, Roberto Nascimento, Roque-Barreira, Maria Cristina
Publicado 2015

Disruption of Active Trans-Sialidase Genes Impairs Egress from Mammalian Host Cells and Generates Highly Attenuated Trypanosoma cruzi Parasites

por Burle-Caldas, Gabriela de A., dos Santos, Nailma S. A., de Castro, Júlia T., Mugge, Fernanda L. B., Grazielle-Silva, Viviane, Oliveira, Antônio Edson R., Pereira, Milton C. A., Reis-Cunha, João Luís, dos Santos, Anderson Coqueiro, Gomes, Dawidson Assis, Bartholomeu, Daniella C., Moretti, Nilmar S., Schenkman, Sergio, Gazzinelli, Ricardo T., Teixeira, Santuza M. R.
Publicado 2022