Cryo-EM as a tool to study bacterial efflux systems and the membrane proteome

por Klenotic, Philip A, Morgan, Christopher E, Yu, Edward W
Publicado 2021

Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity

por Zhang, Zhemin, Morgan, Christopher E., Cui, Meng, Yu, Edward W.
Publicado 2023

Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump

por Zhang, Zhemin, Morgan, Christopher E., Bonomo, Robert A., Yu, Edward W.
Publicado 2023

Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii

por Zhang, Zhemin, Morgan, Christopher E., Bonomo, Robert A., Yu, Edward W.
Publicado 2021

An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

por Morgan, Christopher E., Zhang, Zhemin, Bonomo, Robert A., Yu, Edward W.
Publicado 2022

Toward structural-omics of the bovine retinal pigment epithelium

por Morgan, Christopher E., Zhang, Zhemin, Miyagi, Masaru, Golczak, Marcin, Yu, Edward W.
Publicado 2022

A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes

por Tringides, Marios L, Zhang, Zhemin, Morgan, Christopher E, Su, Chih-Chia, Yu, Edward W
Publicado 2022

Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance

por Zhang, Zhemin, Lizer, Nicholas, Wu, Zuowei, Morgan, Christopher E., Yan, Yuqi, Zhang, Qijing, Yu, Edward W.
Publicado 2023

Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport

por Su, Chih-Chia, Klenotic, Philip A., Cui, Meng, Lyu, Meinan, Morgan, Christopher E., Yu, Edward W.
Publicado 2021

A “Build and Retrieve” methodology to simultaneously solve cryo-EM structures of membrane proteins

por Su, Chih-Chia, Lyu, Meinan, Morgan, Christopher E., Bolla, Jani Reddy, Robinson, Carol V., Yu, Edward W.
Publicado 2021

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development

por Morgan, Christopher E., Huang, Wei, Rudin, Susan D., Taylor, Derek J., Kirby, James E., Bonomo, Robert A., Yu, Edward W.
Publicado 2020

Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates

por Morgan, Christopher E., Glaza, Przemyslaw, Leus, Inga V., Trinh, Anhthu, Su, Chih-Chia, Cui, Meng, Zgurskaya, Helen I., Yu, Edward W.
Publicado 2021

Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump

por Su, Chih-Chia, Morgan, Christopher E., Kambakam, Sekhar, Rajavel, Malligarjunan, Scott, Harry, Huang, Wei, Emerson, Corey C., Taylor, Derek J., Stewart, Phoebe L., Bonomo, Robert A., Yu, Edward W.
Publicado 2019

Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome

por Morgan, Christopher E., Kang, Yoon-Suk, Green, Alex B., Smith, Kenneth P., Dowgiallo, Matthew G., Miller, Brandon C., Chiaraviglio, Lucius, Truelson, Katherine A., Zulauf, Katelyn E., Rodriguez, Shade, Kang, Anthony D., Manetsch, Roman, Yu, Edward W., Kirby, James E.
Publicado 2023