Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to “B” or Not to “B”: Is That Still the Question?

por Leete, Pia, Morgan, Noel G.
Publicado 2021

Fifty years of pancreatic islet pathology in human type 1 diabetes: insights gained and progress made

por Morgan, Noel G., Richardson, Sarah J.
Publicado 2018

Enteroviral infections in the pathogenesis of type 1 diabetes: new insights for therapeutic intervention

por Richardson, Sarah J, Morgan, Noel G
Publicado 2018

Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection

por Akhbari, Pouria, Richardson, Sarah J, Morgan, Noel G
Publicado 2020

The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes

por Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.
Publicado 2023

Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells

por Russell, Mark A., Cooper, Angela C., Dhayal, Shalinee, Morgan, Noel G.
Publicado 2013

Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death

por Thomas, Patricia, Leslie, Kaiyven A., Welters, Hannah J., Morgan, Noel G.
Publicado 2021

Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns

por Jeffery, Nicola, Richardson, Sarah, Chambers, David, Morgan, Noel G, Harries, Lorna W
Publicado 2019

Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes

por Wedgwood, Kyle C. A., Richardson, Sarah J., Morgan, Noel G., Tsaneva-Atanasova, Krasimira
Publicado 2016

The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes

por Leslie, Kaiyven A., Russell, Mark A., Taniguchi, Kazuto, Richardson, Sarah J., Morgan, Noel G.
Publicado 2018

Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells

por Thomas, Patricia, Arden, Catherine, Corcoran, Jenna, Hacker, Christian, Welters, Hannah J., Morgan, Noel G.
Publicado 2022

Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas

por Morgan, Noel G., Richardson, Sarah J., Powers, Alvin C., Saunders, Diane C., Brissova, Marcela
Publicado 2022

Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line

por Keane, Deirdre C., Takahashi, Hilton K., Dhayal, Shalinee, Morgan, Noel G., Curi, Rui, Newsholme, Philip
Publicado 2010

Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic β-cells

por Diakogiannaki, Eleftheria, Dhayal, Shalinee, Childs, Caroline E, Calder, Philip C, Welters, Hannah J, Morgan, Noel G
Publicado 2007

Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes

por Willcox, Abby, Richardson, Sarah J., Walker, Lucy S. K., Kent, Sally C., Morgan, Noel G., Gillespie, Kathleen M.
Publicado 2017

HLA Class I Upregulation and Antiviral Immune Responses in Graves Disease

por Weider, Therese, Richardson, Sarah J, Morgan, Noel G, Paulsen, Trond H, Dahl-Jørgensen, Knut, Hammerstad, Sara Salehi
Publicado 2020

Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes

por Dharmadhikari, Gitanjali, Stolz, Katharina, Hauke, Michael, Morgan, Noel G., Varki, Ajit, de Koning, Eelco, Kelm, Sørge, Maedler, Kathrin
Publicado 2017

Temporal regulation of interferon signalling in human EndoC-βH1 cells

por Dhayal, Shalinee, Leslie, Kaiyven Afi, Baity, Mohammad, Akhbari, Pouria, Richardson, Sarah J, Russell, Mark A, Morgan, Noel G
Publicado 2022

Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity

por Bahal, Sameer, Houssen, Maha E., Manson, Ania, Lorenzo, Lorena, Russell, Mark A., Morgan, Noel G., Tahami, Fariba, Grigoriadou, Sofia
Publicado 2019

Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes

por Boldison, Joanne, Hopkinson, Jessica R., Davies, Joanne, Pearson, James A., Leete, Pia, Richardson, Sarah, Morgan, Noel G., Wong, F. Susan
Publicado 2022