The worm sheds light on anesthetic mechanisms

por Singaram, Vinod K., Morgan, Philip G., Sedensky, Margaret M.
Publicado 2012

Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain

por Kayser, Ernst-Bernhard, Sedensky, Margaret M., Morgan, Philip G.
Publicado 2016

Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

por Quintana, Albert, Morgan, Philip G., Kruse, Shane E., Palmiter, Richard D., Sedensky, Margaret M.
Publicado 2012

Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity

por Ramadasan-Nair, Renjini, Hui, Jessica, Zimin, Pavel I., Itsara, Leslie S., Morgan, Philip G., Sedensky, Margaret M.
Publicado 2017

AGING AND MITOCHONDRIAL DISEASE: SHARED MECHANISMS AND THERAPIES?

por Bitto, Alessandro, Tung, Herman, Ying, Kejun, Smith, Daniel L, Kayser, Ernst-Bernhard, Morgan, Philip G, Sedensky, Margaret M, Kaeberlein, Matt
Publicado 2019

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

por Spencer, Kira A., Mulholland, Michael, Snell, John, Howe, Miranda, James, Katerina, Hanaford, Allison R., Morgan, Philip G., Sedensky, Margaret, Johnson, Simon C.
Publicado 2023

A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer

por Burman, Jonathon L., Itsara, Leslie S., Kayser, Ernst-Bernhard, Suthammarak, Wichit, Wang, Adrienne M., Kaeberlein, Matt, Sedensky, Margaret M., Morgan, Philip G., Pallanck, Leo J.
Publicado 2014

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

por Johnson, Simon C., Pan, Amanda, Sun, Grace X., Freed, Arielle, Stokes, Julia C., Bornstein, Rebecca, Witkowski, Michael, Li, Li, Ford, Jeremy M., Howard, Christopher R. A., Sedensky, Margaret M., Morgan, Philip G.
Publicado 2019

Leukocytes mediate disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome

por Stokes, Julia C., Bornstein, Rebecca L., James, Katerina, Park, Kyung Yeon, Spencer, Kira A., Vo, Katie, Snell, John C., Johnson, Brittany M., Morgan, Philip G., Sedensky, Margaret M., Baertsch, Nathan A., Johnson, Simon C.
Publicado 2022

Mechanisms underlying neonate-specific metabolic effects of volatile anesthetics

por Stokes, Julia, Freed, Arielle, Bornstein, Rebecca, Su, Kevin N, Snell, John, Pan, Amanda, Sun, Grace X, Park, Kyung Yeon, Jung, Sangwook, Worstman, Hailey, Johnson, Brittany M, Morgan, Philip G, Sedensky, Margaret M, Johnson, Simon C
Publicado 2021

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans

por Bennett, Christopher F., Kwon, Jane J., Chen, Christine, Russell, Joshua, Acosta, Kathlyn, Burnaevskiy, Nikolay, Crane, Matthew M., Bitto, Alessandro, Vander Wende, Helen, Simko, Marissa, Pineda, Victor, Rossner, Ryan, Wasko, Brian M., Choi, Haeri, Chen, Shiwen, Park, Shirley, Jafari, Gholamali, Sands, Bryan, Perez Olsen, Carissa, Mendenhall, Alexander R., Morgan, Philip G., Kaeberlein, Matt
Publicado 2017