Fast Skeletal Muscle Troponin Activator tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1(G93A) ALS Mouse Model

por Hwee, Darren T., Kennedy, Adam, Ryans, Julie, Russell, Alan J., Jia, Zhiheng, Hinken, Aaron C., Morgans, David J., Malik, Fady I., Jasper, Jeffrey R.
Publicado 2014

Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension

por Ho, David, Chen, Li, Zhao, Xin, Durham, Nicquanna, Pannirselvam, Malar, Vatner, Dorothy E., Morgans, David J., Malik, Fady I., Vatner, Stephen F., Shen, You-Tang
Publicado 2012

Tirasemtiv amplifies skeletal muscle response to nerve activation in humans

por Hansen, Richard, Saikali, Khalil G, Chou, Willis, Russell, Alan J, Chen, Michael M, Vijayakumar, Vipin, Stoltz, Randall R, Baudry, Stephane, Enoka, Roger M, Morgans, David J, Wolff, Andrew A, Malik, Fady I
Publicado 2014

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator

por Collibee, Scott E., Bergnes, Gustave, Muci, Alexander, Browne, William F., Garard, Marc, Hinken, Aaron C., Russell, Alan J., Suehiro, Ion, Hartman, James, Kawas, Raja, Lu, Pu-Ping, Lee, Kenneth H., Marquez, David, Tomlinson, Matthew, Xu, Donghong, Kennedy, Adam, Hwee, Darren, Schaletzky, Julia, Leung, Kwan, Malik, Fady I., Morgans, David J., Morgan, Bradley P.
Publicado 2018

Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

por Russell, Alan J, Hartman, James J, Hinken, Aaron C, Muci, Alexander R, Kawas, Raja, Driscoll, Lena, Godinez, Guillermo, Lee, Kenneth H, Marquez, David, Browne, William F, Chen, Michael M, Clarke, David, Collibee, Scott E, Garard, Marc, Hansen, Richard, Jia, Zhiheng, Lu, Pu-Ping, Rodriguez, Hector, Saikali, Khalil G, Schaletzky, Julia, Vijayakumar, Vipin, Albertus, Daniel L, Claflin, Dennis R, Morgans, David J, Morgan, Bradley P, Malik, Fady I
Publicado 2012

Dual inhibition of α(v)β(6) and α(v)β(1) reduces fibrogenesis in lung tissue explants from patients with IPF

por Decaris, Martin L., Schaub, Johanna R., Chen, Chun, Cha, Jacob, Lee, Gail G., Rexhepaj, Megi, Ho, Steve S., Rao, Vikram, Marlow, Megan M., Kotak, Prerna, Budi, Erine H., Hooi, Lisa, Wu, Jianfeng, Fridlib, Marina, Martin, Shamra P., Huang, Shaoyi, Chen, Ming, Muñoz, Manuel, Hom, Timothy F., Wolters, Paul J., Desai, Tushar J., Rock, Fernando, Leftheris, Katerina, Morgans, David J., Lepist, Eve-Irene, Andre, Patrick, Lefebvre, Eric A., Turner, Scott M.
Publicado 2021