The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena

por Linger, Benjamin R., Morin, Gregg B., Price, Carolyn M.
Publicado 2011

Tandem mass tag-based thermal proteome profiling for the discovery of drug-protein interactions in cancer cells

por Johnson, Fraser D., Hughes, Christopher S., Liu, Alvin, Lockwood, William W., Morin, Gregg B.
Publicado 2023

The FUS-DDIT3 Interactome in Myxoid Liposarcoma()

por Yu, Jamie S.E., Colborne, Shane, Hughes, Christopher S., Morin, Gregg B., Nielsen, Torsten O.
Publicado 2019

Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding

por Dixon-Clarke, Sarah E., Elkins, Jonathan M., Cheng, S.-W. Grace, Morin, Gregg B., Bullock, Alex N.
Publicado 2015

The Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB

por DeVorkin, Lindsay, Go, Nancy Erro, Hou, Ying-Chen Claire, Moradian, Annie, Morin, Gregg B., Gorski, Sharon M.
Publicado 2014

Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research

por Hughes, Christopher S., McConechy, Melissa K., Cochrane, Dawn R., Nazeran, Tayyebeh, Karnezis, Anthony N., Huntsman, David G., Morin, Gregg B.
Publicado 2016

Hsp83 loss suppresses proteasomal activity resulting in an upregulation of caspase-dependent compensatory autophagy

por Choutka, Courtney, DeVorkin, Lindsay, Go, Nancy Erro, Hou, Ying-Chen Claire, Moradian, Annie, Morin, Gregg B., Gorski, Sharon M.
Publicado 2017

Modification of the Creator recombination system for proteomics applications – improved expression by addition of splice sites

por Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, Hardy, W Rod, Pawson, Tony, Morin, Gregg B
Publicado 2006

Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma

por Gibb, Ewan A, Warren, René L, Wilson, Gavin W, Brown, Scott D, Robertson, Gordon A, Morin, Gregg B, Holt, Robert A
Publicado 2015

The Oncogenic Roles of DICER1 RNase IIIb Domain Mutations in Ovarian Sertoli-Leydig Cell Tumors()()

por Wang, Yemin, Chen, Jiamin, Yang, Winnie, Mo, Fan, Senz, Janine, Yap, Damian, Anglesio, Michael S., Gilks, Blake, Morin, Gregg B., Huntsman, David G.
Publicado 2015

Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress

por Mathew, Veena, Tam, Annie S., Milbury, Karissa L., Hofmann, Analise K., Hughes, Christopher S., Morin, Gregg B., Loewen, Christopher J.R., Stirling, Peter C.
Publicado 2017

Human antibodies targeting ENPP1 as candidate therapeutics for cancers

por Chu, Xiaojie, Baek, Du-San, Li, Wei, Shyp, Taras, Mooney, Brian, Hines, Margaret G., Morin, Gregg B., Sorensen, Poul H., Dimitrov, Dimiter S.
Publicado 2023

The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer

por Chern, Yi-Jye, Wong, John C. T., Cheng, Grace S. W., Yu, Angel, Yin, Yaling, Schaeffer, David F., Kennecke, Hagen F., Morin, Gregg, Tai, Isabella T.
Publicado 2019

The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy

por Chittaranjan, Suganthi, Xu, Jing, Kuzyk, Michael, Dullat, Harpreet K., Wilton, James, DeVorkin, Lindsay, Lebovitz, Chandra, Morin, Gregg B., Marra, Marco A., Gorski, Sharon M.
Publicado 2015

MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation

por Pon, Julia R., Wong, Jackson, Saberi, Saeed, Alder, Olivia, Moksa, Michelle, Grace Cheng, S. -W., Morin, Gregg B., Hoodless, Pamela A., Hirst, Martin, Marra, Marco A.
Publicado 2015

De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer

por Lefort, Sylvain, El-Naggar, Amal, Tan, Susanna, Colborne, Shane, Negri, Gian Luca, Pellacani, Davide, Hirst, Martin, Gusterson, Barry, Morin, Gregg B., Sorensen, Poul H., Eaves, Connie J.
Publicado 2021

Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes

por Asleh, Karama, Negri, Gian Luca, Spencer Miko, Sandra E., Colborne, Shane, Hughes, Christopher S., Wang, Xiu Q., Gao, Dongxia, Gilks, C. Blake, Chia, Stephen K. L., Nielsen, Torsten O., Morin, Gregg B.
Publicado 2022

Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases

por Owen, Daniel R., Wong, Hui-li, Bonakdar, Melika, Jones, Martin, Hughes, Christopher S., Morin, Gregg B., Jones, Steven J.M., Renouf, Daniel J., Lim, Howard, Laskin, Janessa, Marra, Marco, Yip, Stephen, Schaeffer, David F.
Publicado 2018

CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion

por Tien, Jerry F., Mazloomian, Alborz, Cheng, S.-W. Grace, Hughes, Christopher S., Chow, Christalle C.T., Canapi, Leanna T., Oloumi, Arusha, Trigo-Gonzalez, Genny, Bashashati, Ali, Xu, James, Chang, Vicky C.-D., Shah, Sohrab P., Aparicio, Samuel, Morin, Gregg B.
Publicado 2017

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity

por Chittaranjan, Suganthi, Chan, Susanna, Yang, Cindy, Yang, Kevin C., Chen, Vincent, Moradian, Annie, Firme, Marlo, Song, Jungeun, Go, Nancy E., Blough, Michael D., Chan, Jennifer A., Cairncross, J. Gregory, Gorski, Sharon M., Morin, Gregg B., Yip, Stephen, Marra, Marco A.
Publicado 2014