Genome-Wide Modulation of Gene Transcription in Ovarian Carcinoma Cells by a New Mithramycin Analogue

por Vizcaíno, Carolina, Núñez, Luz-Elena, Morís, Francisco, Portugal, José
Publicado 2014

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

por Pandiella, Atanasio, Morís, Francisco, Ocaña, Alberto, Núñez, Luz-Elena, Montero, Juan C.
Publicado 2015

The NFκB pathway: a therapeutic target in glioblastoma

por Nogueira, Lorena, Ruiz-Ontañon, Patricia, Vazquez-Barquero, Alfonso, Moris, Francisco, Fernandez-Luna, Jose L.
Publicado 2011

Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations

por Martinez-Cruzado, Lucia, Tornin, Juan, Santos, Laura, Rodriguez, Aida, García-Castro, Javier, Morís, Francisco, Rodriguez, Rene
Publicado 2016

New Insights into the Biosynthesis Pathway of Polyketide Alkaloid Argimycins P in Streptomyces argillaceus

por Ye, Suhui, Braña, Alfredo F., González-Sabín, Javier, Morís, Francisco, Olano, Carlos, Salas, José A., Méndez, Carmen
Publicado 2018

Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma

por Federico, Aniello, Steinfass, Tamara, Larribère, Lionel, Novak, Daniel, Morís, Francisco, Núñez, Luz-Elena, Umansky, Viktor, Utikal, Jochen
Publicado 2020

Modulation of the Activity of Sp Transcription Factors by Mithramycin Analogues as a New Strategy for Treatment of Metastatic Prostate Cancer

por Malek, Anastasia, Núñez, Luz-Elena, Magistri, Marco, Brambilla, Lara, Jovic, Sandra, Carbone, Giuseppina M., Morís, Francisco, Catapano, Carlo V.
Publicado 2012

The chromomycin CmmA acetyltransferase: a membrane‐bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

por García, Beatriz, González‐Sabín, Javier, Menéndez, Nuria, Braña, Alfredo F., Núñez, Luz Elena, Morís, Francisco, Salas, José A., Méndez, Carmen
Publicado 2011

Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine Alkaloids Argimycins P

por Ye, Suhui, Molloy, Brian, Braña, Alfredo F., Zabala, Daniel, Olano, Carlos, Cortés, Jesús, Morís, Francisco, Salas, José A., Méndez, Carmen
Publicado 2017

Pleiotropic Anti-Angiogenic and Anti-Oncogenic Activities of the Novel Mithralog Demycarosyl-3D-ß-D-Digitoxosyl-Mithramycin SK (EC-8042)

por Fernández-Guizán, Azahara, López-Soto, Alejandro, Acebes-Huerta, Andrea, Huergo-Zapico, Leticia, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo
Publicado 2015

DESign of Sustainable One-Pot Chemoenzymatic Organic Transformations in Deep Eutectic Solvents for the Synthesis of 1,2-Disubstituted Aromatic Olefins

por Ríos-Lombardía, Nicolás, Rodríguez-Álvarez, María Jesús, Morís, Francisco, Kourist, Robert, Comino, Natalia, López-Gallego, Fernando, González-Sabín, Javier, García-Álvarez, Joaquín
Publicado 2020

Expanding the Toolbox of R‐Selective Amine Transaminases by Identification and Characterization of New Members

por Telzerow, Aline, Paris, Juraj, Håkansson, Maria, González‐Sabín, Javier, Ríos‐Lombardía, Nicolas, Gröger, Harald, Morís, Francisco, Schürmann, Martin, Schwab, Helmut, Steiner, Kerstin
Publicado 2020

Nano-Encapsulation of Mithramycin in Transfersomes and Polymeric Micelles for the Treatment of Sarcomas

por Estupiñán, Óscar, Rendueles, Claudia, Suárez, Paula, Rey, Verónica, Murillo, Dzohara, Morís, Francisco, Gutiérrez, Gemma, Blanco-López, María del Carmen, Matos, María, Rodríguez, René
Publicado 2021

Chemoenzymatic Approaches to the Synthesis of the Calcimimetic Agent Cinacalcet Employing Transaminases and Ketoreductases

por Marx, Lisa, Ríos‐Lombardía, Nicolás, Farnberger, Judith F., Kroutil, Wolfgang, Benítez‐Mateos, Ana I., López‐Gallego, Fernando, Morís, Francisco, González‐Sabín, Javier, Berglund, Per
Publicado 2018

Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

por Serrano-Heras, Gemma, Cuenca-López, María Dolores, Montero, Juan Carlos, Corrales-Sanchez, Verónica, Morales, Jorge Carlos, Núñez, Luz-Elena, Morís, Francisco, Pandiella, Atanasio, Ocaña, Alberto
Publicado 2015

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

por Tornin, Juan, Martinez-Cruzado, Lucia, Santos, Laura, Rodriguez, Aida, Núñez, Luz-Elena, Oro, Patricia, Hermosilla, Maria Ana, Allonca, Eva, Fernández-García, Maria Teresa, Astudillo, Aurora, Suarez, Carlos, Morís, Francisco, Rodriguez, Rene
Publicado 2016

High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

por Buchmann, Anina, Eitel, Michael, Koch, Pierre, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Wolański, Marcin, Krawiec, Michał, Zakrzewska-Czerwińska, Jolanta, Méndez, Carmen, Botas, Alma, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Gross, Harald
Publicado 2016

A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

por Wolański, Marcin, Krawiec, Michał, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Buchmann, Anina, Gross, Harald, Eitel, Michael, Koch, Pierre, Botas, Alma, Méndez, Carmen, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Zakrzewska‐Czerwińska, Jolanta
Publicado 2020

The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling

por Lorenzo-Herrero, Seila, Sordo-Bahamonde, Christian, Bretones, Gabriel, Payer, Ángel R., González-Rodríguez, Ana P., González-García, Esther, Pérez-Escuredo, Jhudit, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo, López-Soto, Alejandro
Publicado 2019

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

por Cuenca-López, María Dolores, Serrano-Heras, Gemma, Montero, Juan Carlos, Corrales-Sánchez, Verónica, Gomez-Juarez, Mónica, Gascón-Escribano, Maria José, Carlos Morales, Jorge, Voisin, Veronique, Núñez, Luz Elena, Morís, Francisco, Bader, Gary D., Pandiella, Atanasio, Ocaña, Alberto
Publicado 2015