The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model

por Kermanizadeh, Ali, Brown, David M., Moritz, Wolfgang, Stone, Vicki
Publicado 2019

Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an...

por Kermanizadeh, Ali, Berthing, Trine, Guzniczak, Ewa, Wheeldon, Melanie, Whyte, Graeme, Vogel, Ulla, Moritz, Wolfgang, Stone, Vicki
Publicado 2019

Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH

por Kermanizadeh, Ali, Valli, Jessica, Sanchez, Katarzyna, Hutter, Simon, Pawlowska, Agnieszka, Whyte, Graeme, Moritz, Wolfgang, Stone, Vicki
Publicado 2021

NMR microsystem for label-free characterization of 3D nanoliter microtissues

por Grisi, Marco, Conley, Gaurasundar M., Rodriguez, Kyle J., Riva, Erika, Egli, Lukas, Moritz, Wolfgang, Lichtenberg, Jan, Brugger, Jürgen, Boero, Giovanni
Publicado 2020

Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues

por Messner, Simon, Fredriksson, Lisa, Lauschke, Volker M., Roessger, Katrin, Escher, Claudia, Bober, Magdalena, Kelm, Jens M., Ingelman-Sundberg, Magnus, Moritz, Wolfgang
Publicado 2018

Comparing in vitro human liver models to in vivo human liver using RNA-Seq

por Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian
Publicado 2020

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

por Krebs, Alice, van Vugt-Lussenburg, Barbara M. A., Waldmann, Tanja, Albrecht, Wiebke, Boei, Jan, ter Braak, Bas, Brajnik, Maja, Braunbeck, Thomas, Brecklinghaus, Tim, Busquet, Francois, Dinnyes, Andras, Dokler, Joh, Dolde, Xenia, Exner, Thomas E., Fisher, Ciarán, Fluri, David, Forsby, Anna, Hengstler, Jan G., Holzer, Anna-Katharina, Janstova, Zofia, Jennings, Paul, Kisitu, Jaffar, Kobolak, Julianna, Kumar, Manoj, Limonciel, Alice, Lundqvist, Jessica, Mihalik, Balázs, Moritz, Wolfgang, Pallocca, Giorgia, Ulloa, Andrea Paola Cediel, Pastor, Manuel, Rovida, Costanza, Sarkans, Ugis, Schimming, Johannes P., Schmidt, Bela Z., Stöber, Regina, Strassfeld, Tobias, van de Water, Bob, Wilmes, Anja, van der Burg, Bart, Verfaillie, Catherine M., von Hellfeld, Rebecca, Vrieling, Harry, Vrijenhoek, Nanette G., Leist, Marcel
Publicado 2020