Requirement for the eIF4E Binding Proteins for the Synergistic Down-Regulation of Protein Synthesis by Hypertonic Conditions and mTOR Inhibition

por Clemens, Michael J., Elia, Androulla, Morley, Simon J.
Publicado 2013

mTOR inhibition and levels of the DNA repair protein MGMT in T98G glioblastoma cells

por Smalley, Sarah, Chalmers, Anthony J, Morley, Simon J
Publicado 2014

mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation

por Pollard, Hilary J, Willett, Mark, Morley, Simon J
Publicado 2014

Sumoylation of eIF4A2 affects stress granule formation

por Jongjitwimol, Jirapas, Baldock, Robert A., Morley, Simon J., Watts, Felicity Z.
Publicado 2016

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells

por Lineham, Ella, Tizzard, Graham J., Coles, Simon J., Spencer, John, Morley, Simon J.
Publicado 2018

The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading

por Copsey, Alice C., Cooper, Simon, Parker, Robert, Lineham, Ella, Lapworth, Cuzack, Jallad, Deema, Sweet, Steve, Morley, Simon J.
Publicado 2017

Probing the Anticancer Action of Novel Ferrocene Analogues of MNK Inhibitors

por Sansook, Supojjanee, Lineham, Ella, Hassell-Hart, Storm, Tizzard, Graham J., Coles, Simon J., Spencer, John, Morley, Simon J.
Publicado 2018

Murine Norovirus 1 (MNV1) Replication Induces Translational Control of the Host by Regulating eIF4E Activity during Infection

por Royall, Elizabeth, Doyle, Nicole, Abdul-Wahab, Azimah, Emmott, Ed, Morley, Simon J., Goodfellow, Ian, Roberts, Lisa O., Locker, Nicolas
Publicado 2015

SMG-1 and mTORC1 Act Antagonistically to Regulate Response to Injury and Growth in Planarians

por González-Estévez, Cristina, Felix, Daniel A., Smith, Matthew D., Paps, Jordi, Morley, Simon J., James, Victoria, Sharp, Tyson V., Aboobaker, A. Aziz
Publicado 2012

The S. pombe Translation Initiation Factor eIF4G Is Sumoylated and Associates with the SUMO Protease Ulp2

por Jongjitwimol, Jirapas, Feng, Min, Zhou, Lihong, Wilkinson, Oliver, Small, Lauren, Baldock, Robert, Taylor, Deborah L., Smith, Duncan, Bowler, Lucas D., Morley, Simon J., Watts, Felicity Z.
Publicado 2014

Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism

por Towler, Benjamin P., Pashler, Amy L., Haime, Hope J., Przybyl, Katarzyna M., Viegas, Sandra C., Matos, Rute G., Morley, Simon J., Arraiano, Cecilia M., Newbury, Sarah F.
Publicado 2020