Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

por Kardon, Julia R, Moroco, Jamie A, Engen, John R, Baker, Tania A
Publicado 2020

Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement

por Moroco, Jamie A., Craigo, Jodi K., Iacob, Roxana E., Wales, Thomas E., Engen, John R., Smithgall, Thomas E.
Publicado 2014

Design of Stapled Antimicrobial Peptides that Overcome Antibiotic Resistance and In Vivo Toxicity

por Mourtada, Rida, Herce, Henry D., Yin, Daniel J., Moroco, Jamie A., Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2019

HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck

por Pene-Dumitrescu, Teodora, Shu, Sherry T, Wales, Thomas E, Alvarado, John J, Shi, Haibin, Narute, Purushottam, Moroco, Jamie A, Yeh, Joanne I, Engen, John R, Smithgall, Thomas E
Publicado 2012

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

por Prew, Michelle S., Camara, Christina M., Botzanowski, Thomas, Moroco, Jamie A., Bloch, Noah B., Levy, Hannah R., Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Bird, Gregory H., Herce, Henry D., Gygi, Micah A., Escudero, Silvia, Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2022

Allosteric control of Ubp6 and the proteasome via a bidirectional switch

por Hung, Ka Ying Sharon, Klumpe, Sven, Eisele, Markus R., Elsasser, Suzanne, Tian, Geng, Sun, Shuangwu, Moroco, Jamie A., Cheng, Tat Cheung, Joshi, Tapan, Seibel, Timo, Van Dalen, Duco, Feng, Xin-Hua, Lu, Ying, Ovaa, Huib, Engen, John R., Lee, Byung-Hoon, Rudack, Till, Sakata, Eri, Finley, Daniel
Publicado 2022

Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state

por Miller, Peter G., Sathappa, Murugappan, Moroco, Jamie A., Jiang, Wei, Qian, Yue, Iqbal, Sumaiya, Guo, Qi, Giacomelli, Andrew O., Shaw, Subrata, Vernier, Camille, Bajrami, Besnik, Yang, Xiaoping, Raffier, Cerise, Sperling, Adam S., Gibson, Christopher J., Kahn, Josephine, Jin, Cyrus, Ranaghan, Matthew, Caliman, Alisha, Brousseau, Merissa, Fischer, Eric S., Lintner, Robert, Piccioni, Federica, Campbell, Arthur J., Root, David E., Garvie, Colin W., Ebert, Benjamin L.
Publicado 2022