Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening

por Morreale, Francesca E., Bortoluzzi, Alessio, Chaugule, Viduth K., Arkinson, Connor, Walden, Helen, Ciulli, Alessio
Publicado 2017

Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements

por Morreale, Francesca E., Testa, Andrea, Chaugule, Viduth K., Bortoluzzi, Alessio, Ciulli, Alessio, Walden, Helen
Publicado 2017

BacPROTACs mediate targeted protein degradation in bacteria

por Morreale, Francesca E., Kleine, Stefan, Leodolter, Julia, Junker, Sabryna, Hoi, David M., Ovchinnikov, Stepan, Okun, Anastasia, Kley, Juliane, Kurzbauer, Robert, Junk, Lukas, Guha, Somraj, Podlesainski, David, Kazmaier, Uli, Boehmelt, Guido, Weinstabl, Harald, Rumpel, Klaus, Schmiedel, Volker M., Hartl, Markus, Haselbach, David, Meinhart, Anton, Kaiser, Markus, Clausen, Tim
Publicado 2022