Coronary Artery Disease–Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes

por Morris, Gavin E., Braund, Peter S., Moore, Jasbir S., Samani, Nilesh J., Codd, Veryan, Webb, Tom R.
Publicado 2017

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

por Morris, Gavin E., Nelson, Carl P., Standen, Nicholas B., Challiss, R.A. John, Willets, Jonathon M.
Publicado 2010

G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

por Morris, Gavin E., Nelson, Carl P., Everitt, Diane, Brighton, Paul J., Standen, Nicholas B., Challiss, R.A. John, Willets, Jonathon M.
Publicado 2011

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

por Bridge, Jack C., Aylott, Jonathan W., Brightling, Christopher E., Ghaemmaghami, Amir M., Knox, Alan J., Lewis, Mark P., Rose, Felicity R.A.J., Morris, Gavin E.
Publicado 2015

HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis

por Aravani, Dimitra, Morris, Gavin E., Jones, Peter D., Tattersall, Helena K., Karamanavi, Elisavet, Kaiser, Michael A., Kostogrys, Renata B., Ghaderi Najafabadi, Maryam, Andrews, Sarah L., Nath, Mintu, Ye, Shu, Stringer, Emma J., Samani, Nilesh J., Webb, Tom R.
Publicado 2019

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

por Chernyavsky, Igor L., Russell, Richard J., Saunders, Ruth M., Morris, Gavin E., Berair, Rachid, Singapuri, Amisha, Chachi, Latifa, Mansur, Adel H., Howarth, Peter H., Dennison, Patrick, Chaudhuri, Rekha, Bicknell, Stephen, Rose, Felicity R.A.J., Siddiqui, Salman, Brook, Bindi S., Brightling, Christopher E.
Publicado 2018

The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1

por Morris, Gavin E., Denniff, Matthew J., Karamanavi, Elisavet, Andrews, Sarah A., Kostogrys, Renata B., Bountziouka, Vasiliki, Ghaderi‐Najafabadi, Maryam, Shamkhi, Noor, McConnell, George, Kaiser, Michael A., Carleton, Laura, Schofield, Christine, Kessler, Thorsten, Rainbow, Richard D., Samani, Nilesh J., Webb, Thomas R.
Publicado 2022

The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis

por Karamanavi, Elisavet, McVey, David G., van der Laan, Sander W., Stanczyk, Paulina J., Morris, Gavin E., Wang, Yifan, Yang, Wei, Chan, Kenneth, Poston, Robin N., Luo, Jun, Zhou, Xinmiao, Gong, Peng, Jones, Peter D., Cao, Junjun, Kostogrys, Renata B., Webb, Tom R., Pasterkamp, Gerard, Yu, Haojie, Xiao, Qingzhong, Greer, Peter A., Stringer, Emma J., Samani, Nilesh J., Ye, Shu
Publicado 2022