Arid1a restrains Kras-dependent changes in acinar cell identity

por Livshits, Geulah, Alonso-Curbelo, Direna, Morris, John P, Koche, Richard, Saborowski, Michael, Wilkinson, John Erby, Lowe, Scott W
Publicado 2018

A modular and flexible ESC-based mouse model of pancreatic cancer

por Saborowski, Michael, Saborowski, Anna, Morris, John P., Bosbach, Benedikt, Dow, Lukas E., Pelletier, Jerry, Klimstra, David S., Lowe, Scott W.
Publicado 2014

Expanded RNA-binding activities of mammalian Argonaute 2

por Tan, Grace S., Garchow, Barry G., Liu, Xuhang, Yeung, Jennifer, Morris, John P., Cuellar, Trinna L., McManus, Michael T., Kiriakidou, Marianthi
Publicado 2009

Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition

por Chen, Chong, Liu, Yu, Lu, Chao, Cross, Justin R., Morris, John P., Shroff, Aditya S., Ward, Patrick S., Bradner, James E., Thompson, Craig, Lowe, Scott W.
Publicado 2013

Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation

por Morris, John P., Greer, Renee, Russ, Holger A., von Figura, Guido, Kim, Grace E., Busch, Anke, Lee, Jonghyeob, Hertel, Klemens J., Kim, Seung, Mcmanus, Michael, Hebrok, Matthias
Publicado 2014

A combinatorial strategy for treating KRAS mutant lung cancer

por Manchado, Eusebio, Weissmueller, Susann, Morris, John P., Chen, Chi-Chao, Wullenkord, Ramona, Lujambio, Amaia, de Stanchina, Elisa, Poirier, John T., Gainor, Justin F., Corcoran, Ryan B., Engelman, Jeffrey A., Rudin, Charles M., Rosen, Neal, Lowe, Scott W.
Publicado 2016

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

por Zhu, Changyu, Soto-Feliciano, Yadira M, Morris, John P, Huang, Chun-Hao, Koche, Richard P, Ho, Yu-jui, Banito, Ana, Chen, Chun-Wei, Shroff, Aditya, Tian, Sha, Livshits, Geulah, Chen, Chi-Chao, Fennell, Myles, Armstrong, Scott A, Allis, C David, Tschaharganeh, Darjus F, Lowe, Scott W
Publicado 2023

A gene-environment induced epigenetic program initiates tumorigenesis

por Alonso-Curbelo, Direna, Ho, Yu-Jui, Burdziak, Cassandra, Maag, Jesper L.V., Morris, John P., Chandwani, Rohit, Chen, Hsuan-An, Tsanov, Kaloyan M., Barriga, Francisco M., Luan, Wei, Tasdemir, Nilgun, Livshits, Geulah, Azizi, Elham, Chun, Jaeyoung, Wilkinson, John E., Mazutis, Linas, Leach, Steven D., Koche, Richard, Pe’er, Dana, Lowe, Scott W.
Publicado 2021

A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets

por Li, Xiang, Huang, Chun-Hao, Sánchez-Rivera, Francisco J., Kennedy, Margaret C., Tschaharganeh, Darjus F., Morris, John P., Montinaro, Antonella, O'Rourke, Kevin P., Banito, Ana, Wilkinson, John E., Chen, Chi-Chao, Ho, Yu-Jui, Dow, Lukas E., Tian, Sha, Luan, Wei, de Stanchina, Elisa, Zhang, Tinghu, Gray, Nathanael S., Walczak, Henning, Lowe, Scott W.
Publicado 2022

Ordered and deterministic cancer genome evolution after p53 loss

por Baslan, Timour, Morris, John P., Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M., Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M., Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J., Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark T. A., Socci, Nicholas D., Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D., Iacobuzio-Donahue, Christine A., Lowe, Scott W.
Publicado 2022