Organophosphorus Flame Retardants Inhibit Specific Liver Carboxylesterases and Cause Serum Hypertriglyceridemia

por Morris, Patrick J., Medina-Cleghorn, Daniel, Heslin, Ann, King, Sarah M., Orr, Joseph, Mulvihill, Melinda M., Krauss, Ronald M., Nomura, Daniel K.
Publicado 2014

Chemical Genetics Screening Reveals KIAA1363 as a Cytokine-Lowering Target

por Hunerdosse, Devon M., Morris, Patrick J., Miyamoto, David K., Fisher, Karl J., Bateman, Leslie A., Ghazaleh, Jonathan R., Zhong, Sharon, Nomura, Daniel K.
Publicado 2014

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

por Venkatesh, Humsa S., Tam, Lydia T., Woo, Pamelyn J., Lennon, James, Nagaraja, Surya, Gillespie, Shawn M., Ni, Jing, Duveau, Damien Y., Morris, Patrick J., Zhao, Jean J., Thomas, Craig J., Monje, Michelle
Publicado 2017

Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

por Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael
Publicado 2021

Time will tell. Reply to “Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.” by Chen et al

por Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael
Publicado 2022

Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration

por Moaddel, Ruin, Zanos, Panos, Farmer, Cristan A., Kadriu, Bashkim, Morris, Patrick J., Lovett, Jacqueline, Acevedo-Diaz, Elia E., Cavanaugh, Grace W., Yuan, Peixiong, Yavi, Mani, Thomas, Craig J., Park, Lawrence T., Ferrucci, Luigi, Gould, Todd D., Zarate, Carlos A.
Publicado 2022

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential

por Meyer, Sara E., Muench, David E., Rogers, Andrew M., Newkold, Tess J., Orr, Emily, O’Brien, Eric, Perentesis, John P., Doench, John G., Lal, Ashish, Morris, Patrick J., Thomas, Craig J., Lieberman, Judy, McGlinn, Edwina, Aronow, Bruce J., Salomonis, Nathan, Grimes, H. Leighton
Publicado 2018

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

por Sayin, Volkan I, LeBoeuf, Sarah E, Singh, Simranjit X, Davidson, Shawn M, Biancur, Douglas, Guzelhan, Betul S, Alvarez, Samantha W, Wu, Warren L, Karakousi, Triantafyllia R, Zavitsanou, Anastasia Maria, Ubriaco, Julian, Muir, Alexander, Karagiannis, Dimitris, Morris, Patrick J, Thomas, Craig J, Possemato, Richard, Vander Heiden, Matthew G, Papagiannakopoulos, Thales
Publicado 2017

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

por Zanos, Panos, Moaddel, Ruin, Morris, Patrick J., Georgiou, Polymnia, Fischell, Jonathan, Elmer, Greg I., Alkondon, Manickavasagom, Yuan, Peixiong, Pribut, Heather J., Singh, Nagendra S., Dossou, Katina S.S., Fang, Yuhong, Huang, Xi-Ping, Mayo, Cheryl L., Wainer, Irving W., Albuquerque, Edson X., Thompson, Scott M., Thomas, Craig J., Zarate, Carlos A., Gould, Todd D.
Publicado 2016

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection

por Nelson, Elizabeth A., Dyall, Julie, Hoenen, Thomas, Barnes, Alyson B., Zhou, Huanying, Liang, Janie Y., Michelotti, Julia, Dewey, William H., DeWald, Lisa Evans, Bennett, Richard S., Morris, Patrick J., Guha, Rajarshi, Klumpp-Thomas, Carleen, McKnight, Crystal, Chen, Yu-Chi, Xu, Xin, Wang, Amy, Hughes, Emma, Martin, Scott, Thomas, Craig, Jahrling, Peter B., Hensley, Lisa E., Olinger, Gene G., White, Judith M.
Publicado 2017

High-potency ligands for DREADD imaging and activation in rodents and monkeys

por Bonaventura, Jordi, Eldridge, Mark A. G., Hu, Feng, Gomez, Juan L., Sanchez-Soto, Marta, Abramyan, Ara M., Lam, Sherry, Boehm, Matthew A., Ruiz, Christina, Farrell, Mitchell R., Moreno, Andrea, Galal Faress, Islam Mustafa, Andersen, Niels, Lin, John Y., Moaddel, Ruin, Morris, Patrick J., Shi, Lei, Sibley, David R., Mahler, Stephen V., Nabavi, Sadegh, Pomper, Martin G., Bonci, Antonello, Horti, Andrew G., Richmond, Barry J., Michaelides, Michael
Publicado 2019

Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo

por Finch, Courtney L., Dyall, Julie, Xu, Shuang, Nelson, Elizabeth A., Postnikova, Elena, Liang, Janie Y., Zhou, Huanying, DeWald, Lisa Evans, Thomas, Craig J., Wang, Amy, Xu, Xin, Hughes, Emma, Morris, Patrick J., Mirsalis, Jon C., Nguyen, Linh H., Arolfo, Maria P., Koci, Bryan, Holbrook, Michael R., Hensley, Lisa E., Jahrling, Peter B., Schmaljohn, Connie, Johansen, Lisa M., Olinger, Gene G., Schiffer, Joshua T., White, Judith M.
Publicado 2021