Using participatory epidemiology to assess factors contributing to common enteric pathogens in Ontario: results from a workshop held at the Ontario Veterinary College, University o...

por Harding, Shannon A, Parmley, E Jane, Morrison, Karen E
Publicado 2014

Extracellular Vesicles in Amyotrophic Lateral Sclerosis

por McCluskey, Gavin, Morrison, Karen E., Donaghy, Colette, Rene, Frederique, Duddy, William, Duguez, Stephanie
Publicado 2022

The Role of Sphingomyelin and Ceramide in Motor Neuron Diseases

por McCluskey, Gavin, Donaghy, Colette, Morrison, Karen E., McConville, John, Duddy, William, Duguez, Stephanie
Publicado 2022

Serum Neurofilaments in Motor Neuron Disease and Their Utility in Differentiating ALS, PMA and PLS

por McCluskey, Gavin, Morrison, Karen E., Donaghy, Colette, McConville, John, McCarron, Mark O., McVerry, Ferghal, Duddy, William, Duguez, Stephanie
Publicado 2023

Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31]

por Al-Chalabi, Ammar, Shaw, Pamela J, Young, Carolyn A, Morrison, Karen E, Murphy, Caroline, Thornhill, Marie, Kelly, Joanna, Steen, I Nicholas, Leigh, P Nigel
Publicado 2011

The Effects of Two Polymorphisms on p21(cip1) Function and Their Association with Alzheimer’s Disease in a Population of European Descent

por Yates, Sharon C., Zafar, Amen, Rabai, Erzsebet M., Foxall, James B., Nagy, Sheila, Morrison, Karen E., Clarke, Carl, Esiri, Margaret M., Christie, Sharon, Smith, A. David, Nagy, Zsuzsanna
Publicado 2015

UK case control study of smoking and risk of amyotrophic lateral sclerosis

por Opie-Martin, Sarah, Jones, Ashley, Iacoangeli, Alfredo, Al-Khleifat, Ahmad, Oumar, Mohamed, Shaw, Pamela J., Shaw, Chris E., Morrison, Karen E., Wootton, Robyn E., Davey-Smith, George, Pearce, Neil, Al-Chalabi, Ammar
Publicado 2020

An Evaluation of a SVA Retrotransposon in the FUS Promoter as a Transcriptional Regulator and Its Association to ALS

por Savage, Abigail L., Wilm, Thomas P., Khursheed, Kejhal, Shatunov, Aleksey, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Smith, Bradley, Breen, Gerome, Al-Chalabi, Ammar, Moss, Diana, Bubb, Vivien J., Quinn, John P.
Publicado 2014

C9orf72 intermediate expansions of 24–30 repeats are associated with ALS

por Iacoangeli, Alfredo, Al Khleifat, Ahmad, Jones, Ashley R., Sproviero, William, Shatunov, Aleksey, Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Fogh, Isabella, Dobson, Richard J., Newhouse, Stephen J., Al-Chalabi, Ammar
Publicado 2019

Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias

por Mehta, Puja R, Jones, Ashley R, Opie-Martin, Sarah, Shatunov, Aleksey, Iacoangeli, Alfredo, Al Khleifat, Ahmad, Smith, Bradley N, Topp, Simon, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Morgan, Sarah, Pittman, Alan, Al-Chalabi, Ammar
Publicado 2019

Telomere length is greater in ALS than in controls: a whole genome sequencing study

por Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Fang, Ton, Sproviero, William, Jones, Ashley R., Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Powell, John F., Dobson, Richard, Newhouse, Steven J., Al-Chalabi, Ammar
Publicado 2019

Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy

por Al-Chalabi, Ammar, Dürr, Alexandra, Wood, Nicholas W., Parkinson, Michael H., Camuzat, Agnes, Hulot, Jean-Sébastien, Morrison, Karen E., Renton, Alan, Sussmuth, Sigurd D., Landwehrmeyer, Bernhard G., Ludolph, Albert, Agid, Yves, Brice, Alexis, Leigh, P. Nigel, Bensimon, Gilbert
Publicado 2009

A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK

por Morgan, Sarah, Shatunov, Aleksey, Sproviero, William, Jones, Ashley R., Shoai, Maryam, Hughes, Deborah, Al Khleifat, Ahmad, Malaspina, Andrea, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Sidle, Katie, Orrell, Richard W., Fratta, Pietro, Hardy, John, Pittman, Alan, Al-Chalabi, Ammar
Publicado 2017

Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)

por Cox, Laura E., Ferraiuolo, Laura, Goodall, Emily F., Heath, Paul R., Higginbottom, Adrian, Mortiboys, Heather, Hollinger, Hannah C., Hartley, Judith A., Brockington, Alice, Burness, Christine E., Morrison, Karen E., Wharton, Stephen B., Grierson, Andrew J., Ince, Paul G., Kirby, Janine, Shaw, Pamela J.
Publicado 2010

Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis

por Gaastra, Benjamin, Shatunov, Aleksey, Pulit, Sara, Jones, Ashley R., Sproviero, William, Gillett, Alexandra, Chen, Zhongbo, Kirby, Janine, Fogh, Isabella, Powell, John F., Leigh, P. Nigel, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., van den Berg, Leonard H., Veldink, Jan H., Lewis, Cathryn M., Al-Chalabi, Ammar
Publicado 2016

Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat

por Jones, Ashley R., Woollacott, Ione, Shatunov, Aleksey, Cooper-Knock, Johnathan, Buchman, Vladimir, Sproviero, William, Smith, Bradley, Scott, Kirsten M., Balendra, Rubika, Abel, Olubunmi, McGuffin, Peter, Ellis, Catherine M., Shaw, Pamela J., Morrison, Karen E., Farmer, Anne, Lewis, Cathryn M., Leigh, P. Nigel, Shaw, Christopher E., Powell, John F., Al-Chalabi, Ammar
Publicado 2013

Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene

por Cooper-Knock, Johnathan, Zhang, Sai, Kenna, Kevin P., Moll, Tobias, Franklin, John P., Allen, Samantha, Nezhad, Helia Ghahremani, Iacoangeli, Alfredo, Yacovzada, Nancy Y., Eitan, Chen, Hornstein, Eran, Ehilak, Eran, Celadova, Petra, Bose, Daniel, Farhan, Sali, Fishilevich, Simon, Lancet, Doron, Morrison, Karen E., Shaw, Christopher E., Al-Chalabi, Ammar, Veldink, Jan H., Kirby, Janine, Snyder, Michael P., Shaw, Pamela J.
Publicado 2020

Rare variant burden analysis within enhancers identifies CAV1 as an ALS risk gene

por Cooper-Knock, Johnathan, Zhang, Sai, Kenna, Kevin P., Moll, Tobias, Franklin, John P., Allen, Samantha, Nezhad, Helia Ghahremani, Iacoangeli, Alfredo, Yacovzada, Nancy Y., Eitan, Chen, Hornstein, Eran, Elhaik, Eran, Celadova, Petra, Bose, Daniel, Farhan, Sali, Fishilevich, Simon, Lancet, Doron, Morrison, Karen E., Shaw, Christopher E., Al-Chalabi, Ammar, Veldink, Jan H., Kirby, Janine, Snyder, Michael P., Shaw, Pamela J.
Publicado 2021

Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies

por Hop, Paul J, Zwamborn, Ramona A J, Hannon, Eilis J, Dekker, Annelot M, van Eijk, Kristel R, Walker, Emma M, Iacoangeli, Alfredo, Jones, Ashley R, Shatunov, Aleksey, Khleifat, Ahmad Al, Opie-Martin, Sarah, Shaw, Christopher E, Morrison, Karen E, Shaw, Pamela J, McLaughlin, Russell L, Hardiman, Orla, Al-Chalabi, Ammar, Van Den Berg, Leonard H, Mill, Jonathan, Veldink, Jan H
Publicado 2020

Safety, Pharmacokinetic, and Functional Effects of the Nogo-A Monoclonal Antibody in Amyotrophic Lateral Sclerosis: A Randomized, First-In-Human Clinical Trial

por Meininger, Vincent, Pradat, Pierre-François, Corse, Andrea, Al-Sarraj, Safa, Rix Brooks, Benjamin, Caress, James B., Cudkowicz, Merit, Kolb, Stephen J., Lange, Dale, Leigh, P. Nigel, Meyer, Thomas, Milleri, Stefano, Morrison, Karen E., Orrell, Richard W., Peters, Gary, Rothstein, Jeffrey D., Shefner, Jeremy, Lavrov, Arseniy, Williams, Nicola, Overend, Phil, Price, Jeffrey, Bates, Stewart, Bullman, Jonathan, Krull, David, Berges, Alienor, Abila, Bams, Meno-Tetang, Guy, Wurthner, Jens
Publicado 2014