Use of a novel rapid and resource-efficient cassette dosing approach to determine the pharmacokinetics and CNS distribution of small molecule 7-transmembrane receptor allosteric mo...

por Bridges, Thomas M, Morrison, Ryan D, Byers, Frank W, Luo, Shuanghui, Scott Daniels, J
Publicado 2014

Analysis of Immune Checkpoint Drug Targets and Tumor Proteotypes in Non-Small Cell Lung Cancer

por Liebler, Daniel C., Holzer, Timothy R., Haragan, Alexander, Morrison, Ryan D., O’Neill Reising, Leslie, Ackermann, Bradley L., Fill, Jeff A., Schade, Andrew E., Gruver, Aaron M.
Publicado 2020

Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring

por Ryan, Timothy P., Morrison, Ryan D., Sutherland, Jeffrey J., Milne, Stephen B., Ryan, Kendall A., Daniels, J. Scott, Misra-Hebert, Anita, Hicks, J. Kevin, Vogan, Eric, Teng, Kathryn, Daly, Thomas M.
Publicado 2017

First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

por Pitchford, Lisa M., Rathmacher, John A., Fuller, John C., Daniels, J. Scott, Morrison, Ryan D., Akers, Wendall S., Abumrad, Naji N., Amarnath, Venkataraman, Currey, Patricia M., Roberts, L. Jackson, Oates, John A., Boutaud, Olivier
Publicado 2019

Accelerated instability testing reveals quantitative mass spectrometry overcomes specimen storage limitations associated with PD-L1 immunohistochemistry

por Haragan, Alexander, Liebler, Daniel C., Das, Dimple M., Soper, Michael D., Morrison, Ryan D., Slebos, Robbert J. C., Ackermann, Bradley L., Fill, Jeff A., Schade, Andrew E., Gosney, John R., Gruver, Aaron M.
Publicado 2020

Proteomic characterisations of ulcerative colitis endoscopic biopsies associate with clinically relevant histological measurements of disease severity

por Gruver, Aaron M, Westfall, Matt D, Ackermann, Bradley L, Hill, Salisha, Morrison, Ryan D, Bodo, Juraj, Lai, Keith K, Gemperline, David C, Hsi, Eric D, Liebler, Daniel C, Schmitz, Jochen, Benschop, Robert J
Publicado 2022

Chemical Modulation of Mutant mGlu(1) Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics

por Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Brogan, John T., Hopkins, Corey R., Niswender, Colleen M., Rodriguez, Alice L., Venable, Daryl F., Morrison, Ryan D., Bubser, Michael, Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado 2014

Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Pep...

por Morris, Lindsey C., Nance, Kellie D., Gentry, Patrick R., Days, Emily L., Weaver, C. David, Niswender, Colleen M., Thompson, Analisa D., Jones, Carrie K., Locuson, Chuck W., Morrison, Ryan D., Daniels, J. Scott, Niswender, Kevin D., Lindsley, Craig W.
Publicado 2014

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Sel...

por Felts, Andrew S., Rodriguez, Alice L., Blobaum, Anna L., Morrison, Ryan D., Bates, Brittney S., Thompson Gray, Analisa, Rook, Jerri M., Tantawy, Mohammed N., Byers, Frank W., Chang, Sichen, Venable, Daryl F., Luscombe, Vincent B., Tamagnan, Gilles D., Niswender, Colleen M., Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A.
Publicado 2017