MYC‐y mice: From tumour initiation to therapeutic targeting of endogenous MYC

por Morton, Jennifer P., Sansom, Owen J.
Publicado 2013

Heterogeneity in Pancreatic Cancer Fibroblasts—TGFβ as a Master Regulator?

por Watt, Dale M., Morton, Jennifer P.
Publicado 2021

RNA polymerase III transcription is repressed in response to the tumour suppressor ARF

por Morton, Jennifer P., Kantidakis, Theodoros, White, Robert J.
Publicado 2007

Neutrophils: Homing in on the myeloid mechanisms of metastasis

por Leach, Joshua, Morton, Jennifer P., Sansom, Owen J.
Publicado 2019

GEMMs as preclinical models for testing pancreatic cancer therapies

por Gopinathan, Aarthi, Morton, Jennifer P., Jodrell, Duncan I., Sansom, Owen J.
Publicado 2015

Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine

por Conway, James RW, Herrmann, David, Evans, TR Jeffry, Morton, Jennifer P, Timpson, Paul
Publicado 2019

MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus

por Godfrey, Jack D., Morton, Jennifer P., Wilczynska, Ania, Sansom, Owen J., Bushell, Martin D.
Publicado 2018

Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging

por Nobis, Max, McGhee, Ewan J, Herrmann, David, Magenau, Astrid, Morton, Jennifer P, Anderson, Kurt I, Timpson, Paul
Publicado 2014

PTEN deficiency permits the formation of pancreatic cancer in the absence of autophagy

por Rosenfeldt, Mathias T, O'Prey, Jim, Flossbach, Lucia, Nixon, Colin, Morton, Jennifer P, Sansom, Owen J, Ryan, Kevin M
Publicado 2017

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

por Ritschka, Birgit, Storer, Mekayla, Mas, Alba, Heinzmann, Florian, Ortells, Mari Carmen, Morton, Jennifer P., Sansom, Owen J., Zender, Lars, Keyes, William M.
Publicado 2017

NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β‐dependent regulation of PLK4

por Whyte, Declan, Skalka, George, Walsh, Peter, Wilczynska, Ania, Paul, Nikki R., Mitchell, Claire, Nixon, Colin, Clarke, William, Bushell, Martin, Morton, Jennifer P., Murphy, Daniel J., Muthalagu, Nathiya
Publicado 2023

Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition

por Michalopoulou, Evdokia, Auciello, Francesca R., Bulusu, Vinay, Strachan, David, Campbell, Andrew D., Tait-Mulder, Jacqueline, Karim, Saadia A., Morton, Jennifer P., Sansom, Owen J., Kamphorst, Jurre J.
Publicado 2020

EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas

por Hill, William, Zaragkoulias, Andreas, Salvador-Barbero, Beatriz, Parfitt, Geraint J., Alatsatianos, Markella, Padilha, Ana, Porazinski, Sean, Woolley, Thomas E., Morton, Jennifer P., Sansom, Owen J., Hogan, Catherine
Publicado 2021

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion

por Gundry, Christine, Marco, Sergi, Rainero, Elena, Miller, Bryan, Dornier, Emmanuel, Mitchell, Louise, Caswell, Patrick T., Campbell, Andrew D., Hogeweg, Anna, Sansom, Owen J., Morton, Jennifer P., Norman, Jim C.
Publicado 2017

Correction: Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1

por Coetzee, Abigail S., Carter, Edward P., Rodríguez-Fernández, Lucía, Heward, James, Wang, Qiaoying, Karim, Saadia A., Boughetane, Lina, Milton, Christopher, Uyulur, Firat, Morton, Jennifer P., Kocher, Hemant M., Grose, Richard P.
Publicado 2023

Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1

por Coetzee, Abigail S., Carter, Edward P., Rodríguez-Fernández, Lucía, Heward, James, Wang, Qiaoying, Karim, Saadia A., Boughetane, Lina, Milton, Christopher, Uyulur, Firat, Morton, Jennifer P., Kocher, Hemant M., Grose, Richard P.
Publicado 2022

Expression of KOC, S100P, mesothelin and MUC1 in pancreatico-biliary adenocarcinomas: development and utility of a potential diagnostic immunohistochemistry panel

por Ali, Asif, Brown, Victoria, Denley, Simon, Jamieson, Nigel B, Morton, Jennifer P, Nixon, Colin, Graham, Janet S, Sansom, Owen J, Carter, C Ross, McKay, Colin J, Duthie, Fraser R, Oien, Karin A
Publicado 2014

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

por Rath, Nicola, Morton, Jennifer P, Julian, Linda, Helbig, Lena, Kadir, Shereen, McGhee, Ewan J, Anderson, Kurt I, Kalna, Gabriela, Mullin, Margaret, Pinho, Andreia V, Rooman, Ilse, Samuel, Michael S, Olson, Michael F
Publicado 2016

CXCR2 inhibition suppresses acute and chronic pancreatic inflammation

por Steele, Colin W, Karim, Saadia A, Foth, Mona, Rishi, Loveena, Leach, Joshua DG, Porter, Ross J, Nixon, Colin, Jeffry Evans, TR, Carter, C Ross, Nibbs, Robert JB, Sansom, Owen J, Morton, Jennifer P
Publicado 2015

Genomic instability in mutant p53 cancer cells upon entotic engulfment

por Mackay, Hannah L., Moore, David, Hall, Callum, Birkbak, Nicolai J., Jamal-Hanjani, Mariam, Karim, Saadia A., Phatak, Vinaya M., Piñon, Lucia, Morton, Jennifer P., Swanton, Charles, Le Quesne, John, Muller, Patricia A. J.
Publicado 2018