Sex-biased autophagy as a potential mechanism mediating sex differences in ischemic stroke outcome

por Noh, Brian, McCullough, Louise D., Moruno-Manchon, Jose F.
Publicado 2022

The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons

por Moruno-Manchon, Jose F., Koellhoffer, Edward C., Gopakumar, Jayakrishnan, Hambarde, Shashank, Kim, Nayun, McCullough, Louise D., Tsvetkov, Andrey S.
Publicado 2017

Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes

por Moruno-Manchon, Jose F., Uzor, Ndidi-Ese, Ambati, Chandrashekar R., Shetty, Vivekananda, Putluri, Nagireddy, Jagannath, Chinnaswamy, McCullough, Louise D., Tsvetkov, Andrey S.
Publicado 2018

Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin

por Escarcega, Rocio Diaz, Patil, Abhijeet A., Moruno-Manchon, Jose F., Urayama, Akihiko, Marrelli, Sean P., Kim, Nayun, Monchaud, David, McCullough, Louise D., Tsvetkov, Andrey S.
Publicado 2023

Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization

por Tabor, Natalie, Ngwa, Conelius, Mitteaux, Jeremie, Meyer, Matthew D., Moruno-Manchon, Jose F., Zhu, Liang, Liu, Fudong, Monchaud, David, McCullough, Louise D., Tsvetkov, Andrey S.
Publicado 2021

Dysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-β in Tg2576 Mice

por Honarpisheh, Pedram, Reynolds, Caroline R., Blasco Conesa, Maria P., Moruno Manchon, Jose F., Putluri, Nagireddy, Bhattacharjee, Meenakshi B., Urayama, Akihiko, McCullough, Louise D., Ganesh, Bhanu P.
Publicado 2020

Sex-Specific Differences in Autophagic Responses to Experimental Ischemic Stroke

por Patrizz, Anthony N., Moruno-Manchon, Jose F., O’Keefe, Lena M., Doran, Sarah J., Patel, Anita R., Venna, Venugopal R., Tsvetkov, Andrey S., Li, Jun, McCullough, Louise D.
Publicado 2021

Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons

por Moruno-Manchon, Jose F, Lejault, Pauline, Wang, Yaoxuan, McCauley, Brenna, Honarpisheh, Pedram, Morales Scheihing, Diego A, Singh, Shivani, Dang, Weiwei, Kim, Nayun, Urayama, Akihiko, Zhu, Liang, Monchaud, David, McCullough, Louise D, Tsvetkov, Andrey S
Publicado 2020