“Glutamatergic-based Rapid Acting Antidepressants: The Link to Synaptic Plasticity”

por Moskal, Joseph R.
Publicado 2017

A prefrontal cortex alpha/delta switch controls the transition from positive to negative affective states

por Burgdorf, Jeffrey S., Moskal, Joseph R.
Publicado 2023

Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome

por Crosson, Lori Ann, Kroes, Roger A., Moskal, Joseph R., Linsenmeier, Robert A.
Publicado 2009

Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina

por Lau, Jennifer C.M., Kroes, Roger A., Moskal, Joseph R., Linsenmeier, Robert A.
Publicado 2013

Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That Exhibits Rapid and Sustained Antidepressant-Like Effects

por Burgdorf, Jeffrey S, Zhang, Xiao-Lei, Stanton, Patric K, Moskal, Joseph R, Donello, John E
Publicado 2022

The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant

por Moskal, Joseph R., Burgdorf, Jeffrey S., Stanton, Patric K., Kroes, Roger A., Disterhoft, John F., Burch, Ronald M., Khan, M. Amin
Publicado 2017

Insulin-Like Growth Factor I Produces an Antidepressant-Like Effect and Elicits N-Methyl-D-Aspartate Receptor Independent Long-Term Potentiation of Synaptic Transmission in Medial...

por Burgdorf, Jeffrey, Zhang, Xiao-lei, Colechio, Elizabeth M., Ghoreishi-Haack, Nayereh, Gross, Amanda, Kroes, Roger A., Stanton, Patric K., Moskal, Joseph R.
Publicado 2015

IGFBP2 Produces Rapid-Acting and Long-Lasting Effects in Rat Models of Posttraumatic Stress Disorder via a Novel Mechanism Associated with Structural Plasticity

por Burgdorf, Jeffrey, Colechio, Elizabeth M., Ghoreishi-Haack, Nayereh, Gross, Amanda L., Rex, Christopher S., Zhang, Xiao-lei, Stanton, Patric K., Kroes, Roger A., Moskal, Joseph R.
Publicado 2017

NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor...

por Bowers, M. Scott, Cacheaux, Luisa P., Sahu, Srishti U., Schmidt, Mary E., Sennello, Joseph A., Leaderbrand, Katherine, Khan, M. Amin, Kroes, Roger A., Moskal, Joseph R.
Publicado 2019

NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory

por Khan, M Amin, Houck, David R, Gross, Amanda L, Zhang, Xiao-lei, Cearley, Cassia, Madsen, Torsten M, Kroes, Roger A, Stanton, Patric K, Burgdorf, Jeffrey, Moskal, Joseph R
Publicado 2017

The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC

por Morrison, Gladys, Asiedu, Marina N., Priebe, Jessica M., Dunning, Jacqueline, Ghoreishi-Haack, Nayereh, Kroes, Roger A., Bowers, M. Scott, Barth, Amanda L., Cearley, Cassia N., Moskal, Joseph R.
Publicado 2019

NMDAR activation regulates the daily rhythms of sleep and mood

por Burgdorf, Jeffrey S, Vitaterna, Martha H, Olker, Christopher J, Song, Eun Joo, Christian, Edward P, Sørensen, Laurits, Turek, Fred W, Madsen, Torsten M, Khan, M Amin, Kroes, Roger A, Moskal, Joseph R
Publicado 2019

Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like Effects

por Donello, John E, Banerjee, Pradeep, Li, Yong-Xin, Guo, Yuan-Xing, Yoshitake, Takashi, Zhang, Xiao-Lei, Miry, Omid, Kehr, Jan, Stanton, Patric K, Gross, Amanda L, Burgdorf, Jeffery S, Kroes, Roger A, Moskal, Joseph R
Publicado 2018