4558 Investigating the functional consequences of anaplastic lymphoma kinase (ALK) mutations arising upon Lorlatinib treatment

por Witek, Gabriela Maria, Miller, Whelton, Slochower, David, Berko, Esther, Mossé, Yael, Lemmon, Mark, Radhakrishnan, Ravi
Publicado 2020

First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot...

por Balis, Frank M., Thompson, Patrick A., Mosse, Yael P., Blaney, Susan M., Minard, Charles G., Weigel, Brenda J., Fox, Elizabeth
Publicado 2016

Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation

por Patil, Keshav, Jordan, Earl Joseph, Park, Jin H., Suresh, Krishna, Smith, Courtney M., Lemmon, Abigail A., Mossé, Yaël P., Lemmon, Mark A., Radhakrishnan, Ravi
Publicado 2021

Dielectrophoretic Capture and Genetic Analysis of Single Neuroblastoma Tumor Cells

por Carpenter, Erica L., Rader, JulieAnn, Ruden, Jacob, Rappaport, Eric F., Hunter, Kristen N., Hallberg, Paul L., Krytska, Kate, O’Dwyer, Peter J., Mosse, Yael P.
Publicado 2014

Heterozygosity mapping for human dominant trait variants

por Imai‐Okazaki, Atsuko, Li, Yi, Horpaopan, Sukanya, Riazalhosseini, Yasser, Garshasbi, Masoud, Mosse, Yael P., Zhang, Di, Schrauwen, Isabelle, Sharma, Aarushi, Fann, Cathy S. J., Leal, Suzanne M., Lathrop, Mark, Ott, Jurg
Publicado 2019

Enrichment of Targetable Mutations in the Relapsed Neuroblastoma Genome

por Padovan-Merhar, Olivia M., Raman, Pichai, Ostrovnaya, Irina, Kalletla, Karthik, Rubnitz, Kaitlyn R., Sanford, Eric M., Ali, Siraj M., Miller, Vincent A., Mossé, Yael P., Granger, Meaghan P., Weiss, Brian, Maris, John M., Modak, Shakeel
Publicado 2016

Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci

por Nguyễn, Lễ B., Diskin, Sharon J., Capasso, Mario, Wang, Kai, Diamond, Maura A., Glessner, Joseph, Kim, Cecilia, Attiyeh, Edward F., Mosse, Yael P., Cole, Kristina, Iolascon, Achille, Devoto, Marcella, Hakonarson, Hakon, Li, Hongzhe K., Maris, John M.
Publicado 2011

Evaluation of the DLL3-targeting Antibody–Drug Conjugate Rovalpituzumab Tesirine in Preclinical Models of Neuroblastoma

por Krytska, Kateryna, Casey, Colleen E., Pogoriler, Jennifer, Martinez, Daniel, Rathi, Komal S., Farrel, Alvin, Berko, Esther R., Tsang, Matthew, Sano, Renata R., Kendsersky, Nathan, Erickson, Stephen W., Teicher, Beverly A., Isse, Kumiko, Saunders, Laura, Smith, Malcolm A., Maris, John M., Mossé, Yael P.
Publicado 2022

OTHR-02. CHIMERIC AURORA A KINASE (AURKA) DEGRADERS EFFICIENTLY TARGET N-MYC

por Valinciute, Gintvile, Eing, Lorenz, Mihalic, Jeffrey, Casey, Colleen E, Tian, Hua, Adhikari, Bikash, Guiducci, Cristiana, Rountree, Ryan, Grohmann, Christoph, Sridharan, Sangita, Lu, Ya-Wen, Vezina-Dawod, Simon, Wegrzyniak, Eric, Chaterjee, Abhinav, Hansen, Gwenn M, Maris, John M, Mossé, Yael P, Eilers, Martin, Wolf, Elmar, Roussel, Martine F
Publicado 2023

Clinical utility of custom-designed NGS panel testing in pediatric tumors

por Surrey, Lea F., MacFarland, Suzanne P., Chang, Fengqi, Cao, Kajia, Rathi, Komal S., Akgumus, Gozde T., Gallo, Daniel, Lin, Fumin, Gleason, Adam, Raman, Pichai, Aplenc, Richard, Bagatell, Rochelle, Minturn, Jane, Mosse, Yael, Santi, Mariarita, Tasian, Sarah K., Waanders, Angela J., Sarmady, Mahdi, Maris, John M., Hunger, Stephen P., Li, Marilyn M.
Publicado 2019

Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma

por Berko, Esther R., Witek, Gabriela M., Matkar, Smita, Petrova, Zaritza O., Wu, Megan A., Smith, Courtney M., Daniels, Alex, Kalna, Joshua, Kennedy, Annie, Gostuski, Ivan, Casey, Colleen, Krytska, Kateryna, Gerelus, Mark, Pavlick, Dean, Ghazarian, Susan, Park, Julie R., Marachelian, Araz, Maris, John M., Goldsmith, Kelly C., Radhakrishnan, Ravi, Lemmon, Mark A., Mossé, Yaël P.
Publicado 2023

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

por Capasso, Mario, Devoto, Marcella, Hou, Cuiping, Asgharzadeh, Shahab, Glessner, Joseph T., Attiyeh, Edward F., Mosse, Yael P., Kim, Cecilia, Diskin, Sharon J., Cole, Kristina A., Bosse, Kristopher, Diamond, Maura, Laudenslager, Marci, Winter, Cynthia, Bradfield, Jonathan P., Scott, Richard H., Jagannathan, Jayanti, Garris, Maria, McConville, Carmel, London, Wendy B., Seeger, Robert C., Grant, Struan F. A., Li, Hongzhe, Rahman, Nazneen, Rappaport, Eric, Hakonarson, Hakon, Maris, John M.
Publicado 2009

Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results

por Goldsmith, Kelly C., Park, Julie R., Kayser, Kimberly, Malvar, Jemily, Chi, Yueh-Yun, Groshen, Susan G., Villablanca, Judith G., Krytska, Kateryna, Lai, Lillian M., Acharya, Patricia T., Goodarzian, Fariba, Pawel, Bruce, Shimada, Hiroyuki, Ghazarian, Susan, States, Lisa, Marshall, Lynley, Chesler, Louis, Granger, Meaghan, Desai, Ami V., Mody, Rajen, Morgenstern, Daniel A., Shusterman, Suzanne, Macy, Margaret E., Pinto, Navin, Schleiermacher, Gudrun, Vo, Kieuhoa, Thurm, Holger C., Chen, Joseph, Liyanage, Marlon, Peltz, Gerson, Matthay, Katherine K., Berko, Esther R., Maris, John M., Marachelian, Araz, Mossé, Yael P.
Publicado 2023

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination

por Ham, Jungoh, Costa, Carlotta, Sano, Renata, Lochmann, Timothy L., Sennott, Erin M., Patel, Neha U., Dastur, Anahita, Gomez-Caraballo, Maria, Krytska, Kateryna, Hata, Aaron N., Floros, Konstantinos V., Hughes, Mark T., Jakubik, Charles T., Heisey, Daniel A.R., Ferrell, Justin T., Bristol, Molly L., March, Ryan J., Yates, Craig, Hicks, Mark A., Nakajima, Wataru, Gowda, Madhu, Windle, Brad E., Dozmorov, Mikhail G., Garnett, Mathew J., McDermott, Ultan, Harada, Hisashi, Taylor, Shirley M., Morgan, Iain M., Benes, Cyril H., Engelman, Jeffrey A., Mossé, Yael P., Faber, Anthony C.
Publicado 2016

The genetic landscape of high-risk neuroblastoma

por Pugh, Trevor J., Morozova, Olena, Attiyeh, Edward F., Asgharzadeh, Shahab, Wei, Jun S., Auclair, Daniel, Carter, Scott L., Cibulskis, Kristian, Hanna, Megan, Kiezun, Adam, Kim, Jaegil, Lawrence, Michael S., Lichenstein, Lee, McKenna, Aaron, Pedamallu, Chandra Sekhar, Ramos, Alex H., Shefler, Erica, Sivachenko, Andrey, Sougnez, Carrie, Stewart, Chip, Ally, Adrian, Birol, Inanc, Chiu, Readman, Corbett, Richard D., Hirst, Martin, Jackman, Shaun D., Kamoh, Baljit, Khodabakshi, Alireza Hadj, Krzywinski, Martin, Lo, Allan, Moore, Richard A., Mungall, Karen L., Qian, Jenny, Tam, Angela, Thiessen, Nina, Zhao, Yongjun, Cole, Kristina A., Diamond, Maura, Diskin, Sharon J., Mosse, Yael P., Wood, Andrew C., Ji, Lingyun, Sposto, Richard, Badgett, Thomas, London, Wendy B., Moyer, Yvonne, Gastier-Foster, Julie M., Smith, Malcolm A., Auvil, Jaime M. Guidry, Gerhard, Daniela S., Hogarty, Michael D., Jones, Steven J. M., Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Seeger, Robert C., Khan, Javed, Marra, Marco A., Meyerson, Matthew, Maris, John M.
Publicado 2013

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

por Rokita, Jo Lynne, Rathi, Komal S., Cardenas, Maria F., Upton, Kristen A., Jayaseelan, Joy, Cross, Katherine L., Pfeil, Jacob, Egolf, Laura E., Way, Gregory P., Farrel, Alvin, Kendsersky, Nathan M., Patel, Khushbu, Gaonkar, Krutika S., Modi, Apexa, Berko, Esther R., Lopez, Gonzalo, Vaksman, Zalman, Mayoh, Chelsea, Nance, Jonas, McCoy, Kristyn, Haber, Michelle, Evans, Kathryn, McCalmont, Hannah, Bendak, Katerina, Böhm, Julia W., Marshall, Glenn M., Tyrrell, Vanessa, Kalletla, Karthik, Braun, Frank K., Qi, Lin, Du, Yunchen, Zhang, Huiyuan, Lindsay, Holly B., Zhao, Sibo, Shu, Jack, Baxter, Patricia, Morton, Christopher, Kurmashev, Dias, Zheng, Siyuan, Chen, Yidong, Bowen, Jay, Bryan, Anthony C., Leraas, Kristen M., Coppens, Sara E., Doddapaneni, HarshaVardhan, Momin, Zeineen, Zhang, Wendong, Sacks, Gregory I., Hart, Lori S., Krytska, Kateryna, Mosse, Yael P., Gatto, Gregory J., Sanchez, Yolanda, Greene, Casey S., Diskin, Sharon J., Vaske, Olena Morozova, Haussler, David, Gastier-Foster, Julie M., E. Anders, Kolb, Gorlick, Richard, Li, Xiao-Nan, Reynolds, C. Patrick, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B., Raman, Pichai, Wheeler, David A., Maris, John M.
Publicado 2019