Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity models

por Motani, Alykhan S, Luo, Jian, Liang, Lingming, Mihalic, Jeffrey T, Chen, Xiaoqi, Tang, Liang, Li, Leping, Jaen, Juan, Chen, Jin-Long, Dai, Kang
Publicado 2013

Distinct Mechanisms for Increased Cardiac Contraction Through Selective Alteration of Either Myosin or Troponin Activity

por Singh, Rohit R., Slater, Rebecca E., Wang, Jinghong, Wang, Chen, Guo, Qi, Motani, Alykhan S., Hartman, James J., Sadayappan, Sakthivel, Ason, Brandon L.
Publicado 2022

Novel Small-Molecule Troponin Activator Increases Cardiac Contractile Function Without Negative Impact on Energetics

por He, Huamei, Baka, Tomas, Balschi, James, Motani, Alykhan S., Nguyen, Kathy K., Liu, Qingxiang, Slater, Rebecca, Rock, Brooke, Wang, Chen, Hale, Christopher, Karamanlidis, Georgios, Hartman, James J., Malik, Fady I., Reagan, Jeff D., Luptak, Ivan
Publicado 2021

Malonyl CoA Decarboxylase Inhibition Improves Cardiac Function Post-Myocardial Infarction

por Wang, Wei, Zhang, Liyan, Battiprolu, Pavan K., Fukushima, Arata, Nguyen, Khanh, Milner, Kenneth, Gupta, Abhishek, Altamimi, Tariq, Byrne, Nikole, Mori, Jun, Alrob, Osama Abo, Wagg, Cory, Fillmore, Natasha, Wang, Shao-hua, Liu, Dongming M., Fu, Angela, Lu, Jenny Yinglin, Chaves, Mary, Motani, Alykhan, Ussher, John R., Reagan, Jeff D., Dyck, Jason R.B., Lopaschuk, Gary D.
Publicado 2019