Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis

por Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Publicado 2011

Development of a ‘clickable’ non-natural nucleotide to visualize the replication of non-instructional DNA lesions

por Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Publicado 2012

Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents

por Choi, Jung-Suk, Kim, Seol, Motea, Edward, Berdis, Anthony
Publicado 2017

Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy

por Singh, Naveen, Pay, S. Louise, Bhandare, Snehal B., Arimpur, Udhaya, Motea, Edward A.
Publicado 2020

XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition

por Patidar, Praveen L., Viera, Talysa, Morales, Julio C., Singh, Naveen, Motea, Edward A., Khandelwal, Megha, Fattah, Farjana J.
Publicado 2020

XRN2 Links Transcription Termination to DNA Damage and Replication Stress

por Morales, Julio C., Richard, Patricia, Patidar, Praveen L., Motea, Edward A., Dang, Tuyen T., Manley, James L., Boothman, David A.
Publicado 2016

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

por Patidar, Praveen L., Motea, Edward A., Fattah, Farjana J., Zhou, Yunyun, Morales, Julio C., Xie, Yang, Garner, Harold R., Boothman, David A.
Publicado 2016

Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer

por Starcher, Colton L., Pay, S. Louise, Singh, Naveen, Yeh, I-Ju, Bhandare, Snehal B., Su, Xiaolin, Huang, Xiumei, Bey, Erik A., Motea, Edward A., Boothman, David A.
Publicado 2020

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

por Morales, Julio C., Richard, Patricia, Rommel, Amy, Fattah, Farjana J., Motea, Edward A., Patidar, Praveen L., Xiao, Ling, Leskov, Konstantin, Wu, Shwu-Yuan, Hittelman, Walter N., Chiang, Cheng-Ming, Manley, James L., Boothman, David A.
Publicado 2014

Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models

por Caston, Rachel A., Shah, Fenil, Starcher, Colton L., Wireman, Randall, Babb, Olivia, Grimard, Michelle, McGeown, Jack, Armstrong, Lee, Tong, Yan, Pili, Roberto, Rupert, Joseph, Zimmers, Teresa A., Elmi, Adily N., Pollok, Karen E., Motea, Edward A., Kelley, Mark R., Fishel, Melissa L.
Publicado 2020