Class IA PI3K regulatory subunits: p110-independent roles and structures

por Fox, Millie, Mott, Helen R., Owen, Darerca
Publicado 2020

Activation of STAT transcription factors by the Rho-family GTPases

por Corry, Jessica, Mott, Helen R., Owen, Darerca
Publicado 2020

The structure and function of protein kinase C-related kinases (PRKs)

por Sophocleous, Georgios, Owen, Darerca, Mott, Helen R.
Publicado 2021

RLIP76: A Structural and Functional Triumvirate

por Cornish, Jasmine, Owen, Darerca, Mott, Helen R.
Publicado 2021

Progress in the therapeutic inhibition of Cdc42 signalling

por Murphy, Natasha P., Mott, Helen R., Owen, Darerca
Publicado 2021

(1)H, (15)N and (13)C resonance assignments of the HR1c domain of PRK1, a protein kinase C-related kinase

por Sophocleous, Georgios, Wood, George, Owen, Darerca, Mott, Helen R.
Publicado 2020

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1

por Watson, Joanna R., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado 2016

NMR resonance assignments for the active and inactive conformations of the small G protein RalA

por Shafiq, Arooj, Campbell, Louise J., Owen, Darerca, Mott, Helen R.
Publicado 2020

Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?

por Cornish, Jasmine, Chamberlain, Samuel G., Owen, Darerca, Mott, Helen R.
Publicado 2020

A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK

por Tetley, George J. N., Mott, Helen R., Cooley, R. Neil, Owen, Darerca
Publicado 2017

Structure determination of the seven-helical transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

por Gautier, Antoine, Mott, Helen R., Bostock, Mark J., Kirkpatrick, John P., Nietlispach, Daniel
Publicado 2010

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

por Rajasekar, Karthik V., Campbell, Louise J., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado 2013

Molecular subversion of Cdc42 signalling in cancer

por Murphy, Natasha P., binti Ahmad Mokhtar, Ana Masara, Mott, Helen R., Owen, Darerca
Publicado 2021

ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer

por Hodder, Samantha, Fox, Millie, Binti Ahmad Mokhtar, Ana Masara, Mott, Helen R., Owen, Darerca
Publicado 2023

Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic region

por Tetley, George J. N., Szeto, Aydan, Fountain, Adam J., Mott, Helen R., Owen, Darerca
Publicado 2018

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

por Hurd, Catherine A., Brear, Paul, Revell, Jefferson, Ross, Sarah, Mott, Helen R., Owen, Darerca
Publicado 2020

Integral membrane protein structure determination using pseudocontact shifts

por Crick, Duncan J., Wang, Jue X., Graham, Bim, Swarbrick, James D., Mott, Helen R., Nietlispach, Daniel
Publicado 2015

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES

por Watson, Joanna R., Fox, Helen M., Nietlispach, Daniel, Gallop, Jennifer L., Owen, Darerca, Mott, Helen R.
Publicado 2016

A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases

por Ahmad Mokhtar, Ana Masara binti, Ahmed, Samrein B. M., Darling, Nicola J., Harris, Matthew, Mott, Helen R., Owen, Darerca
Publicado 2021

Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK

por Clayton, Natasha S., Fox, Millie, Vicenté-Garcia, Jose J., Schroeder, Courtney M., Littlewood, Trevor D., Wilde, Jonathon I., Krishnan, Kadalmani, Brown, Murray J.B., Crafter, Claire, Mott, Helen R., Owen, Darerca
Publicado 2022